Journal article
The Case of the Disappearing Spindle Burst
Neural plasticity, Vol.2016, 8037321
2016
DOI: 10.1155/2016/8037321
PMCID: PMC4826930
PMID: 27119028
Abstract
Sleep spindles are brief cortical oscillations at 10-15 Hz that occur predominantly during non-REM (quiet) sleep in adult mammals and are thought to contribute to learning and memory. Spindle bursts are phenomenologically similar to sleep spindles, but they occur predominantly in early infancy and are triggered by peripheral sensory activity (e.g., by retinal waves); accordingly, spindle bursts are thought to organize neural networks in the developing brain and establish functional links with the sensory periphery. Whereas the spontaneous retinal waves that trigger spindle bursts in visual cortex are a transient feature of early development, the myoclonic twitches that drive spindle bursts in sensorimotor cortex persist into adulthood. Moreover, twitches-and their associated spindle bursts-occur exclusively during REM (active) sleep. Curiously, despite the persistence of twitching into adulthood, twitch-related spindle bursts have not been reported in adult sensorimotor cortex. This raises the question of whether such spindle burst activity does not occur in adulthood or, alternatively, occurs but has yet to be discovered. If twitch-related spindle bursts do occur in adults, they could contribute to the calibration, maintenance, and repair of sensorimotor systems.
Details
- Title: Subtitle
- The Case of the Disappearing Spindle Burst
- Creators
- Alexandre Tiriac - Department of Psychological & Brain Sciences, The University of Iowa, Iowa City, IA 52242, USA; DeLTA Center, The University of Iowa, Iowa City, IA 52242, USAMark S Blumberg - Department of Psychological & Brain Sciences, The University of Iowa, Iowa City, IA 52242, USA; DeLTA Center, The University of Iowa, Iowa City, IA 52242, USA; Department of Biology, The University of Iowa, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Neural plasticity, Vol.2016, 8037321
- DOI
- 10.1155/2016/8037321
- PMID
- 27119028
- PMCID
- PMC4826930
- NLM abbreviation
- Neural Plast
- ISSN
- 2090-5904
- eISSN
- 1687-5443
- Publisher
- United States
- Grant note
- R37 HD081168 / NICHD NIH HHS R37-HD081168 / NICHD NIH HHS
- Language
- English
- Date published
- 2016
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute; Biology
- Record Identifier
- 9984002372602771
Metrics
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