Journal article
The Comprehensive Assessment of Self-Reported Urinary Symptoms: A New Tool for Research on Subtypes of Patients with Lower Urinary Tract Symptoms
The Journal of urology, Vol.201(6), pp.1177-1183
06/2019
DOI: 10.1097/JU.0000000000000140
PMCID: PMC6573020
PMID: 30730410
Abstract
To improve the potential for finding clinically important subtypes of patients with lower urinary tract symptoms we developed the CASUS (Comprehensive Assessment of Self-reported Urinary Symptoms). We used it to present data on the experiences of lower urinary tract symptoms in treatment seeking women and men from a prospective observational cohort. We created an initial list of lower urinary tract symptoms that were confirmed in 22 qualitative interviews with providers, and 88 qualitative interviews with care seeking and noncare seeking women and men with lower urinary tract symptoms. Items from extant measures were adopted and revised, and new items were developed. All items were evaluated for understanding in 64 cognitive interviews. Items were administered to a prospective cohort of female and male patients with lower urinary tract symptoms who were seeking care. Analyses were done to describe item response distributions and correlations among item responses separately for women and men. A total of 444 males and 372 females provided responses to the CASUS. Several sets of items showed different relationships for women compared to men. In particular the associations between sensation related items and incontinence related items were generally positive among females but often negative among males. After using an intensive development process the CASUS addresses a wide range of lower urinary tract symptoms. It should help identify clinically important subtypes of patients. Further, item collection can provide the foundation for shorter measures for use in the clinic and as trial end points.
Details
- Title: Subtitle
- The Comprehensive Assessment of Self-Reported Urinary Symptoms: A New Tool for Research on Subtypes of Patients with Lower Urinary Tract Symptoms
- Creators
- Kevin P Weinfurt - Duke University Medical Center , Durham , North CarolinaJames W Griffith - Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University , Chicago , IllinoisKathryn E Flynn - Medical College of Wisconsin , Milwaukee , WisconsinDavid Cella - Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University , Chicago , IllinoisTamara Bavendam - National Institute of Diabetes and Digestive and Kidney Diseases , Bethesda , MarylandJonathan B Wiseman - Arbor Research Collaborative for Health , Ann Arbor , MichiganVictor P Andreev - Arbor Research Collaborative for Health , Ann Arbor , MichiganH Henry Lai - Washington University School of Medicine , St. Louis , MissouriAlice B Liu - University of Washington , Seattle , WashingtonZiya Kirkali - National Institute of Diabetes and Digestive and Kidney Diseases , Bethesda , MarylandAnne P Cameron - University of Michigan , Ann Arbor , MichiganCatherine S Bradley - Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa , Iowa City , IowaLURN Study Group
- Resource Type
- Journal article
- Publication Details
- The Journal of urology, Vol.201(6), pp.1177-1183
- DOI
- 10.1097/JU.0000000000000140
- PMID
- 30730410
- PMCID
- PMC6573020
- NLM abbreviation
- J Urol
- ISSN
- 0022-5347
- eISSN
- 1527-3792
- Publisher
- United States
- Grant note
- U01 DK100017 / NIDDK NIH HHS U01 DK097779 / NIDDK NIH HHS U01 DK100011 / NIDDK NIH HHS UL1 TR001422 / NCATS NIH HHS K23 DK110417 / NIDDK NIH HHS U01 DK097780 / NIDDK NIH HHS U01 DK099879 / NIDDK NIH HHS U01 DK097772 / NIDDK NIH HHS U01 DK097776 / NIDDK NIH HHS U01 DK099932 / NIDDK NIH HHS
- Language
- English
- Date published
- 06/2019
- Academic Unit
- Epidemiology; Obstetrics and Gynecology; Urology
- Record Identifier
- 9983930393102771
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