Journal article
The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets
British journal of pharmacology, Vol.180(Suppl 2), pp.S1-S22
10/2023
DOI: 10.1111/bph.16176
PMID: 38123153
Abstract
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16176. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are six areas of focus: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
Details
- Title: Subtitle
- The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets
- Creators
- Stephen P H Alexander - University of NottinghamEamonn Kelly - University of BristolAlistair A Mathie - University of SuffolkJohn A Peters - University of DundeeEmma L Veale - Medway School of PharmacyJane F Armstrong - University of EdinburghO Peter Buneman - University of EdinburghElena Faccenda - University of EdinburghSimon D Harding - University of EdinburghMichael Spedding - Spedding Research Solutions SARL, Le Vésinet, 78110, FranceJohn A Cidlowski - National Institutes of HealthDoriano Fabbro - PIQUR Therapeutics (Switzerland)Anthony P Davenport - University of CambridgeJörg Striessnig - Universität InnsbruckJamie A Davies - University of EdinburghKatelin E Ahlers-Dannen - University of IowaMohammed Alqinyah - University of Georgia, Athens, USAThiruma V Arumugam - National University of SingaporeChristopher Bodle - University of PittsburghJosephine Buo Dagner - University of Georgia, Athens, USABandana Chakravarti - University of Iowa, Iowa City, USAShreoshi P Choudhuri - The University of Texas Southwestern Medical CenterKirk M Druey - National Institute of Health, Bethesda, USARory A Fisher - University of IowaKyle J Gerber - Tetracore (United States)John R Hepler - Emory UniversityShelley B Hooks - University of Georgia, Athens, USAHavish S Kantheti - The University of Texas Southwestern Medical CenterBehirda Karaj - University of Michigan, East Lansing, USASomayeh Layeghi-Ghalehsoukhteh - Cobel Darou, Shiraz, IranJae-Kyung Lee - University of Georgia, Athens, USAZili Luo - University of Iowa, Iowa City, USAKirill Martemyanov - Scripps Research InstituteLuke D Mascarenhas - The University of Texas Southwestern Medical CenterHarrison McNabb - Purdue University West LafayetteCarolina Montañez-Miranda - Emory UniversityOsita Ogujiofor - The University of Texas Southwestern Medical CenterHoa Phan - University of Michigan, East Lansing, USADavid L Roman - University of IowaVincent Shaw - Michigan State UniversityBenita Sjogren - Purdue University West LafayetteChristopher Sobey - La Trobe UniversityMackenzie M Spicer - University of IowaKatherine E Squires - Emory UniversityLaurie Sutton - Jupiter (United States)Menbere Wendimu - University of Georgia, Athens, USAThomas Wilkie - The University of Texas Southwestern Medical CenterKeqiang Xie - Scripps Research InstituteQian Zhang - Purdue University West LafayetteYalda Zolghadri - The University of Texas Southwestern Medical Center
- Resource Type
- Journal article
- Publication Details
- British journal of pharmacology, Vol.180(Suppl 2), pp.S1-S22
- DOI
- 10.1111/bph.16176
- PMID
- 38123153
- NLM abbreviation
- Br J Pharmacol
- eISSN
- 1476-5381
- Language
- English
- Date published
- 10/2023
- Academic Unit
- Neurology; Pharmacy; Psychiatry; Critical Care; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Pharmaceutical Sciences and Experimental Therapeutics; Neuroscience and Pharmacology; Medicinal and Natural Products Chemistry; Internal Medicine
- Record Identifier
- 9984533455202771
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