Journal article
The Distribution of Post-Void Residual Volumes in People Seeking Care in the Symptoms of Lower Urinary Tract Dysfunction Network Observational Cohort Study With Comparison to Asymptomatic Populations
Urology (Ridgewood, N.J.), Vol.130, pp.22-28
08/2019
DOI: 10.1016/j.urology.2019.01.069
PMCID: PMC6660395
PMID: 31018115
Abstract
To describe the distribution of post-void residual (PVR) volumes across patients with and without lower urinary tract symptoms (LUTS) and examine relationships between self-reported voiding symptoms, storage symptoms, and PVR.
PVR and demographic data were obtained from the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) observational cohort study. Self-reported symptoms were collected using the American Urological Association Symptom Index and the LUTS Tool. PVR values were obtained from 2 other cohorts: living kidney donors with unknown LUTS from the Renal and Lung Living Donors Evaluation Study (RELIVE), and continent women in the Establishing the Prevalence of Incontinence (EPI) study, a population-based study of racial differences in urinary incontinence prevalence.
Across the 3 studies, median PVRs were similar: 26 mL in LURN (n = 880, range 0-932 mL), 20 mL in EPI (n = 166, range 0-400 mL), and 14 mL in RELIVE (n = 191, range 0-352 mL). In LURN, males had 3.6 times higher odds of having PVR > 200 mL (95% CI = 1.72-7.48). In RELIVE, median PVR was significantly higher for males (20 mL vs 0 mL, P= .004). Among women, only the intermittency severity rating was associated with a probability of an elevated PVR. Among men, incomplete emptying and burning severity rating were associated with a higher odds of elevated PVR, but urgency severity ratings were associated with lower odds of elevated PVR.
Care-seeking patients have PVRs similar to those in people with unknown history of LUTS (RELIVE) and without self-reported LUTS (EPI). Although PVR was correlated with voiding symptoms, the mean differences only explain ∼2% of the variance.
Details
- Title: Subtitle
- The Distribution of Post-Void Residual Volumes in People Seeking Care in the Symptoms of Lower Urinary Tract Dysfunction Network Observational Cohort Study With Comparison to Asymptomatic Populations
- Creators
- Andrew C Peterson - Duke University Medical Center, Durham, NC. Electronic address: drew.peterson@duke.eduAbigail R Smith - Arbor Research Collaborative for Health, Ann Arbor, MIMatthew O Fraser - Duke University Medical Center, Durham, NCClaire C Yang - University of Washington, Seattle, WAJohn O L DeLancey - University of Michigan, Ann Arbor, MIBrenda W Gillespie - University of Michigan, Ann Arbor, MIJohn L Gore - University of Washington, Seattle, WAPooja Talaty - NorthShore University Health System, Glenview, ILVictor P Andreev - Arbor Research Collaborative for Health, Ann Arbor, MIKarl J Kreder - University of Iowa, Iowa City, IAMargaret G Mueller - Northwestern University, Chicago, ILH Henry Lai - Washington University School of Medicine, St. Louis, MOBradley A Erickson - University of Iowa, Iowa City, IAZiya Kirkali - National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
- Resource Type
- Journal article
- Publication Details
- Urology (Ridgewood, N.J.), Vol.130, pp.22-28
- DOI
- 10.1016/j.urology.2019.01.069
- PMID
- 31018115
- PMCID
- PMC6660395
- NLM abbreviation
- Urology
- ISSN
- 0090-4295
- eISSN
- 1527-9995
- Publisher
- United States
- Grant note
- U01 DK100017 / NIDDK NIH HHS U01 DK097779 / NIDDK NIH HHS U01 DK100011 / NIDDK NIH HHS UL1 TR001422 / NCATS NIH HHS K23 DK110417 / NIDDK NIH HHS U01 DK097780 / NIDDK NIH HHS U01 DK099879 / NIDDK NIH HHS U01 DK097772 / NIDDK NIH HHS U01 DK097776 / NIDDK NIH HHS U01 DK099932 / NIDDK NIH HHS
- Language
- English
- Date published
- 08/2019
- Academic Unit
- Obstetrics and Gynecology; Urology
- Record Identifier
- 9984051595202771
Metrics
18 Record Views