Journal article
The Ecoresponsive Genome of Daphnia pulex
Science (American Association for the Advancement of Science), Vol.331(6017), pp.555-561
02/04/2011
DOI: 10.1126/science.1197761
PMCID: PMC3529199
PMID: 21292972
Abstract
We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes. The high gene count is a consequence of an elevated rate of gene duplication resulting in tandem gene clusters. More than a third of Daphnia’s genes have no detectable homologs in any other available proteome, and the most amplified gene families are specific to the Daphnia lineage. The coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random, and the analysis of gene expression under different environmental conditions reveals that numerous paralogs acquire divergent expression patterns soon after duplication. Daphnia-specific genes, including many additional loci within sequenced regions that are otherwise devoid of annotations, are the most responsive genes to ecological challenges.
Details
- Title: Subtitle
- The Ecoresponsive Genome of Daphnia pulex
- Creators
- John K Colbourne - Indiana UniversityMichael E Pfrender - Utah State UniversityDonald Gilbert - Indiana UniversityW. Kelley Thomas - University of New HampshireAbraham Tucker - Indiana UniversityTodd H Oakley - University of California, Santa BarbaraShinichi Tokishita - Tokyo University of Pharmacy and Life SciencesAndrea Aerts - Joint Genome InstituteGeorg J Arnold - Ludwig-Maximilians-Universität MünchenMalay Kumar Basu - National Institutes of HealthDarren J Bauer - University of New HampshireCarla E Cáceres - University of Illinois SystemLiran Carmel - National Institutes of HealthClaudio Casola - Indiana UniversityJeong-Hyeon Choi - Indiana UniversityJohn C Detter - Joint Genome InstituteQunfeng Dong - Indiana UniversitySerge Dusheyko - Joint Genome InstituteBrian D Eads - Indiana UniversityThomas Fröhlich - Ludwig-Maximilians-Universität MünchenKerry A Geiler-Samerotte - University of California, Santa BarbaraDaniel Gerlach - University of GenevaPhil Hatcher - University of New HampshireSanjuro Jogdeo - University of New HampshireJeroen Krijgsveld - Utrecht UniversityEvgenia V Kriventseva - University of GenevaDietmar Kültz - University of California, DavisChristian Laforsch - Ludwig-Maximilians-Universität MünchenErika Lindquist - Joint Genome InstituteJacqueline Lopez - Indiana UniversityJ. Robert ManakJean Muller - European Molecular Biology LaboratoryJasmyn Pangilinan - Joint Genome InstituteRupali P Patwardhan - Indiana UniversitySamuel Pitluck - Joint Genome InstituteEllen J Pritham - The University of Texas at ArlingtonAndreas Rechtsteiner - Indiana University BloomingtonMina Rho - Indiana UniversityIgor B Rogozin - United States National Library of MedicineOnur Sakarya - University of California, Santa BarbaraAsaf Salamov - Joint Genome InstituteSarah Schaack - Indiana UniversityHarris Shapiro - Joint Genome InstituteYasuhiro Shiga - Tokyo University of Pharmacy and Life SciencesCourtney SkalitzkyZachary Smith - Indiana UniversityAlexander Souvorov - United States National Library of MedicineWay Sung - University of New HampshireZuojian Tang - Indiana UniversityDai Tsuchiya - Indiana UniversityHank Tu - Joint Genome InstituteHarmjan Vos - Utrecht UniversityMei Wang - Joint Genome InstituteYuri I Wolf - United States National Library of MedicineHideo Yamagata - Tokyo University of Pharmacy and Life SciencesTakuji Yamada - European Molecular Biology LaboratoryYuzhen Ye - Indiana UniversityJoseph R Shaw - Indiana UniversityJusten Andrews - Indiana UniversityTeresa J Crease - University of GuelphHaixu Tang - Indiana UniversitySusan M Lucas - Joint Genome InstituteHugh M Robertson - University of Illinois Urbana-ChampaignPeer Bork - European Molecular Biology LaboratoryEugene V Koonin - United States National Library of MedicineEvgeny M Zdobnov - University of GenevaIgor V Grigoriev - Joint Genome InstituteMichael Lynch - Indiana UniversityJeffrey L Boore - Joint Genome Institute
- Resource Type
- Journal article
- Publication Details
- Science (American Association for the Advancement of Science), Vol.331(6017), pp.555-561
- DOI
- 10.1126/science.1197761
- PMID
- 21292972
- PMCID
- PMC3529199
- NLM abbreviation
- Science
- ISSN
- 0036-8075
- eISSN
- 1095-9203
- Grant note
- R24 GM078274-01A1 || GM / National Institute of General Medical Sciences : NIGMS P42 ES004699-25 || ES / National Institute of Environmental Health Sciences : NIEHS
- Language
- English
- Date published
- 02/04/2011
- Academic Unit
- Stead Family Department of Pediatrics; Biology; Craniofacial Anomalies Research Center
- Record Identifier
- 9984217422802771
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