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The Editors' Choice
Journal article   Open access   Peer reviewed

The Editors' Choice

Cezmi A Akdis and Zuhair K Ballas
Journal of allergy and clinical immunology, Vol.137(2), p.377
02/01/2016
DOI: 10.1016/j.jaci.2015.12.1297
PMID: 26853129
url
https://doi.org/10.1016/j.jaci.2015.12.1297View
Published (Version of record) Open Access

Abstract

Cord blood vitamin D, epigenetic deregulation, and wheeze Although a beneficial effect of vitamin D on health is widely accepted, its role in allergy development is still controversial. [...]a deeper mechanistic understanding of how vitamin D is related to immune regulation and allergic inflammation, especially in the perinatal period, is required. [...]this model might represent a method to identify novel types of SCID and a system for preclinical testing of gene therapy for immune deficiencies.
Studies Vitamin D Disease Immunotherapy DNA methylation Epigenetics Clinical trials Inflammation Mutation Allergies

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