Journal article
The Editors' Choice
Journal of allergy and clinical immunology, Vol.137(4), p.1015
04/01/2016
DOI: 10.1016/j.jaci.2016.02.007
PMID: 27059728
Abstract
Concurrently, repeated antigen ingestion triggers a significant accumulation of intestinal CD4+ TH2 cells, which enable ILC2 residents to respond to IL-25 stimulation by producing large amounts of IL-13, resulting in the development of experimental food allergy. [...]IL-25-mediated collaborative interactions between innate ILC2s and adaptive CD4+ TH2 cells appear to be a pivotal step in amplifying the cascade of allergic reactions to ingested antigens. [...]the nasal epithelial barrier is impaired in patients with AR.
Details
- Title: Subtitle
- The Editors' Choice
- Creators
- Cezmi A AkdisZuhair K Ballas
- Resource Type
- Journal article
- Publication Details
- Journal of allergy and clinical immunology, Vol.137(4), p.1015
- Publisher
- Elsevier Limited
- DOI
- 10.1016/j.jaci.2016.02.007
- PMID
- 27059728
- ISSN
- 0091-6749
- eISSN
- 1097-6825
- Language
- English
- Date published
- 04/01/2016
- Academic Unit
- Immunology; Internal Medicine
- Record Identifier
- 9984094534602771
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