The Editors' Choice

Cezmi Akdis; Zuhair Ballas

doi:10.1016/j.jaci.2016.09.012

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Journal article

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Peer reviewed

The Editors' Choice

Cezmi Akdis and Zuhair Ballas

Journal of allergy and clinical immunology, Vol.138(5), p.1299

11/01/2016

DOI: 10.1016/j.jaci.2016.09.012

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Abstract

[...]occurring genetic variations in 2 alcohol dehydrogenase genes, ADH1B (rs1220084) and ADH1C (rs698), were used as proxies for high and low alcohol consumption in adulthood to investigate the possible causal relationship of high alcohol consumption with high IgE levels and allergic disease. High alcohol consumption was associated observationally and genetically with high IgE levels but not with high risk of allergic disease. [...]high alcohol consumption seems to cause high IgE levels, but the increased IgE level does not seem to lead to high risk of allergic disease.

Alcohol

Allergies

Asthma

Biomarkers

Blood platelets

Disease

Inflammation

Mutation

Nitric oxide

Obesity

Patients

Proteins

Rubella

Studies

Details

Title: Subtitle: The Editors' Choice
Creators: Cezmi Akdis
Zuhair Ballas
Resource Type: Journal article
Publication Details: Journal of allergy and clinical immunology, Vol.138(5), p.1299
Publisher: Elsevier Limited
DOI: 10.1016/j.jaci.2016.09.012
ISSN: 0091-6749
eISSN: 1097-6825
Language: English
Date published: 11/01/2016
Academic Unit: Immunology; Internal Medicine
Record Identifier: 9984359677302771

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