Journal article
The Effect of Anesthesia on the Immune System in Colorectal Cancer Patients
Canadian journal of gastroenterology & hepatology, Vol.2018, pp.1-8
04/01/2018
DOI: 10.1155/2018/7940603
PMCID: PMC5899868
PMID: 29805965
Abstract
Colorectal cancer (CRC) is the key leading cause of high morbidity and mortality worldwide. Surgical excision is the most effective treatment for CRC. However, stress caused by surgery response can destroy the body’s immunity and increase the likelihood of cancer dissemination and metastasis. Anesthesia is an effective way to control the stress response, and recent basic and clinical research has shown that anesthesia and related drugs can directly or indirectly affect the immune system of colorectal cancer patients during the perioperative period. Thus, these drugs may affect the prognosis of CRC surgery patients. This review is intended to summarize currently available data regarding the effects of anesthetics and related drugs on perioperative immune function and postoperative recurrence and metastasis in CRC patients. Determining the most suitable anesthesia for patients with CRC is of utmost importance.
Details
- Title: Subtitle
- The Effect of Anesthesia on the Immune System in Colorectal Cancer Patients
- Creators
- Yangjie Dang - Department of Anesthesiology Xi’an Children’s Hospital Xi’an Shaanxi 710032 China xachyy.comXingxing Shi - Department of Anesthesiology Xi’an Children’s Hospital Xi’an Shaanxi 710032 China xachyy.comWilliam Xu - Department of Anesthesiology Carver College of Medicine University of Iowa Iowa City IA 52246 USA uiowa.eduMingzhang Zuo - Department of Anesthesiology Beijing Hospital National Center of Gerontology No. 1 Dahua Road Dongdan Beijing 100730 China bjhmoh.cn
- Contributors
- Yixin E Yang (Editor)
- Resource Type
- Journal article
- Publication Details
- Canadian journal of gastroenterology & hepatology, Vol.2018, pp.1-8
- DOI
- 10.1155/2018/7940603
- PMID
- 29805965
- PMCID
- PMC5899868
- NLM abbreviation
- Can J Gastroenterol Hepatol
- ISSN
- 2291-2789
- eISSN
- 2291-2797
- Publisher
- Hindawi
- Grant note
- 81774415 / National Natural Science Foundation of China
- Language
- English
- Date published
- 04/01/2018
- Academic Unit
- Iowa Neuroscience Institute; Anesthesia
- Record Identifier
- 9984006462902771
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