The Effect of Geniglossal Advancement on Airway Flow Using a Computational Flow Dynamics Model

Aaron Fletcher; Jiwoong Choi; Maged Awadalla; Andrea E. Potash; Tanner J. Wallen; Steven Fletcher; Eugene H. Chang

doi:10.1002/lary.24203

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The Effect of Geniglossal Advancement on Airway Flow Using a Computational Flow Dynamics Model

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The Effect of Geniglossal Advancement on Airway Flow Using a Computational Flow Dynamics Model

Aaron Fletcher, Jiwoong Choi, Maged Awadalla, Andrea E. Potash, Tanner J. Wallen, Steven Fletcher and Eugene H. Chang

The Laryngoscope, Vol.123(12), pp.3227-3232

12/01/2013

DOI: 10.1002/lary.24203

PMCID: PMC3783525

PMID: 23686418

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https://www.ncbi.nlm.nih.gov/pmc/articles/3783525View

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Abstract

Objectives/HypothesisObstructive sleep apnea (OSA) is a sleep disorder caused by partial or complete collapse of the pharyngeal airway. Genioglossal advancement (GGA) is a well-tolerated surgical procedure intended to address hypopharyngeal collapse, yet there are few studies that monitor changes in airflow dynamics at this site. Computation fluid dynamics (CFD) utilizes airflow simulation to predict changes in airflow after anatomic manipulation. Study DesignWe investigated the change in volume and airflow dynamics of the pharyngeal airway after GGA in a cadaveric model. MethodsWe performed serial GGA from 1 mm (control) to 3, 7, and 9 mm on a lightly preserved cadaver. After each intervention, we performed high-resolution computed tomography scans, reconstructed the pharyngeal airway, and quantified airspace volume and CFD analysis with both laminar and large eddy simulation models. ResultsAirway volume increased with linear GGA. In both CFD simulation models, velocity increased and pressure decreased after 9-mm advancement secondary to increased airway diameter and less abrupt changes in airway geometry. ConclusionsThese results suggest that GGA may be effective in increasing airway volume and flow to address hypopharyngeal obstruction in OSA. Level of EvidenceN/A. Laryngoscope, 123:3227-3232, 2013

Life Sciences & Biomedicine

Medicine, Research & Experimental

Otorhinolaryngology

Research & Experimental Medicine

Science & Technology

Details

Title: Subtitle: The Effect of Geniglossal Advancement on Airway Flow Using a Computational Flow Dynamics Model
Creators: Aaron Fletcher - University of Iowa
Jiwoong Choi - University of Iowa
Maged Awadalla - University of Iowa
Andrea E. Potash - University of Iowa
Tanner J. Wallen - University of Iowa
Steven Fletcher - Roy J. and Lucille A. Carver College of Medicine
Eugene H. Chang - Univ Iowa, Dept Otolaryngol Head & Neck Surg, Iowa City, IA 52242 USA
Resource Type: Journal article
Publication Details: The Laryngoscope, Vol.123(12), pp.3227-3232
DOI: 10.1002/lary.24203
PMID: 23686418
PMCID: PMC3783525
NLM abbreviation: Laryngoscope
ISSN: 0023-852X
eISSN: 1531-4995
Publisher: Wiley
Number of pages: 6
Grant note: K08DE021413 / NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Dental & Craniofacial Research (NIDCR) DE021413-01A1 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA KL2RR024980 / NATIONAL CENTER FOR RESEARCH RESOURCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) KL2RR024980 / University of Iowa CTSA
Language: English
Date published: 12/01/2013
Academic Unit: Oral and Maxillofacial Surgery; Mechanical Engineering
Record Identifier: 9984367645402771

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