Journal article
The Effect of Pulsed Electromagnetic Field and Combined Magnetic Field Exposure Time on Healing of a Rabbit Tibial Osteotomy
The Iowa orthopaedic journal, Vol.39(2), pp.20-26
01/01/2019
PMCID: PMC7047300
PMID: 32577103
Appears in Diamond Open Access
Abstract
Background: This study compares effectiveness of two commercially available signals, Pulsed Electromagnetic Field (PEMF) and Combined Magnetic Field (CMF) clinical signals, to stimulate bone healing in rabbit tibial osteotomies.
Methods: One millimeter osteotomies in New Zealand White rabbits, stabilized with external fixators, were exposed daily to either signal for 30 minutes, three or six hours. Osteotomized sham controls received no signal exposure. Analyses of torsional strength, periosteal callus area and fracture healing stage demonstrated dose responses to increasing daily exposures to both signals.
Results: By 14 days torsional strength increased over shams in the three and six hour-treated groups, significant only for the six hour groups (p<0.05). By 21 days both three and six hour-treated groups were significantly stronger than shams (p<0.05, p<0.005) and the PEMF 30 minute treated group also showed significance (p<0.05). PEMF versus CMF-treated groups were not different at any exposure time.
Conclusions: Both CMF and PEMF signals were most effective in this model when used for six hours per day.
Clinical relevance: In this model we demonstrate that though both PEMF and CMF are "bioactive" and promote healing at shorter and longer exposure dosages, there exists an "optimal" threshold effect of 6 hours/day electromagnetic wave stimulation for bone healing.
Keywords: Combined Magnetic Field; Pulsed Electromagnetic Field; animal model; fracture healing.
Details
- Title: Subtitle
- The Effect of Pulsed Electromagnetic Field and Combined Magnetic Field Exposure Time on Healing of a Rabbit Tibial Osteotomy
- Creators
- Douglas C. Fredericks - University of IowaEmily B. Petersen - Department of Orthopedics and Rehabilitation, The University of Iowa, Iowa City, IA USAMadison Rhodes - University of IowaGrace A. Larew - University of IowaJames V. Nepola - University of Iowa
- Resource Type
- Journal article
- Publication Details
- The Iowa orthopaedic journal, Vol.39(2), pp.20-26
- PMID
- 32577103
- PMCID
- PMC7047300
- NLM abbreviation
- Iowa Orthop J
- ISSN
- 1541-5457
- eISSN
- 1555-1377
- Publisher
- Dept. of Orthopaedics, The University of Iowa; United States
- Language
- English
- Date published
- 01/01/2019
- Academic Unit
- Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center
- Record Identifier
- 9984304725302771
Metrics
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