Journal article
The Effect of Speed-of-Processing Training on Depressive Symptoms in ACTIVE
The journals of gerontology. Series A, Biological sciences and medical sciences, Vol.64A(4), pp.468-472
04/2009
DOI: 10.1093/gerona/gln044
PMCID: PMC2657170
PMID: 19181719
Abstract
Objective
We evaluated the effects of three cognitive training interventions on depressive symptoms at 1 and 5 years.
Methods
Advanced Cognitive Training for Independent and Vital Elderly is a multisite randomized controlled trial (age ≥ 65 years), with four groups (memory, reasoning, speed-of-processing, and no-contact control). Complete data were available for 2,014 (72%) and 1,516 (54%) of 2,802 participants at 1 and 5 years. Separate propensity score models adjusted for potential attrition bias. Clinically important increases in depressive symptoms were defined as: (a) Center for Epidemiological Studies-Depression scale (CES-D)-12 score increases ≥0.5 SD and (b) CES-D-12 score increases ≥1.0 SD. Multivariable logistic regression was used.
Results
The speed-of-processing group (vs the no-contact control group) was 30% less likely to experience clinically important increases in depressive symptoms at 1-year (adjusted odds ratio [AOR] = 0.700, p = .012) and 5-year (AOR = 0.698, p = .023) posttraining for the ≥0.5 SD threshold. Similar results (AOR = .669 with p = .039 at 1 year; AOR = 0.651 with p = .059 at 5 years) were obtained for the ≥1.0 SD threshold. No differences were observed among the control, memory, or reasoning groups at either time period or at either threshold.
Conclusion
The speed-of-processing intervention reduced the risk of clinically important increases in depressive symptoms at 1- and 5-years postbaseline.
Details
- Title: Subtitle
- The Effect of Speed-of-Processing Training on Depressive Symptoms in ACTIVE
- Creators
- Fredric D Wolinsky - 1Iowa City VAMC, IowaMark W Vander Weg - 1Iowa City VAMC, IowaRene Martin - 1Iowa City VAMC, IowaFrederick W Unverzagt - 3Indiana University School of Medicine, IndianapolisKarlene K Ball - 4University of Alabama at BirminghamRichard N Jones - 5Hebrew SeniorLife, Boston, MassachusettsSharon L Tennstedt - 6New England Research Institutes, Boston, Massachusetts
- Resource Type
- Journal article
- Publication Details
- The journals of gerontology. Series A, Biological sciences and medical sciences, Vol.64A(4), pp.468-472
- DOI
- 10.1093/gerona/gln044
- PMID
- 19181719
- PMCID
- PMC2657170
- NLM abbreviation
- J Gerontol A Biol Sci Med Sci
- ISSN
- 1079-5006
- eISSN
- 1758-535X
- Publisher
- Oxford University Press
- Language
- English
- Date published
- 04/2009
- Academic Unit
- Health Management and Policy; Psychological and Brain Sciences; Nursing; Injury Prevention Research Center; Community and Behavioral Health; Internal Medicine
- Record Identifier
- 9984063120802771
Metrics
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