The Effect of Treating Institution on Outcomes in Head and Neck Cancer

Amy Anne D. Lassig; Anne M. Joseph; Bruce R. Lindgren; Patricia Fernandes; Sarah Cooper; Chelsea Schotzko; Samir Khariwala; Margaret Reynolds; Bevan Yueh

doi:10.1177/0194599812457324

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The Effect of Treating Institution on Outcomes in Head and Neck Cancer

Journal article

Peer reviewed

The Effect of Treating Institution on Outcomes in Head and Neck Cancer

Amy Anne D. Lassig, Anne M. Joseph, Bruce R. Lindgren, Patricia Fernandes, Sarah Cooper, Chelsea Schotzko, Samir Khariwala, Margaret Reynolds and Bevan Yueh

Otolaryngology-head and neck surgery, Vol.147(6), pp.1083-1092

12/2012

DOI: 10.1177/0194599812457324

PMCID: PMC5552409

PMID: 22875780

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https://www.ncbi.nlm.nih.gov/pmc/articles/5552409View

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Abstract

Objective. Factors leading patients with head and neck cancer (HNCA) to seek radiation or chemoradiation in an academic center versus the community are incompletely understood, as are the effects of site of treatment on treatment completion and survival. Study Design. Historical cohort study. Setting. Tertiary academic center, community practices. Methods. A historical cohort study was completed of patients with mucosal HNCA identified by International Classification of Disease, Ninth Revision (ICD-9) codes receiving consultation at the authors' institution from 2003 to 2008. Patients who received primary and adjuvant radiation at an academic center or in the community were included. The authors compared treatment completion rates and performed univariate and multivariate analyses of treatment outcomes. Results. Of 388 patients, 210 completed treatment at an academic center and 145 at a community center (33 excluded, location unknown). Patients with HNCA undergoing radiation at an academic site had more advanced disease (P = .024) and were more likely to receive concurrent chemotherapy. Academic hospitals had a higher percentage of noncurrent smokers, higher median income, and higher percentage of oropharyngeal tumors. There was no significant difference in the rate of planned treatment completion between community and academic centers (93.7% vs 94.7%, P > .81) or rate of treatment breaks (22.4% vs 28.4%, P > .28). On Kaplan-Meier analysis, the 5-year survival rate was 53.2% (95% confidence interval [CI], 45.3%-61.1%) for academic centers and 32.8% (95% CI, 22.0%-43.6%) for community hospitals (P < .001). Conclusion. In this cohort, although treatment completion and treatment breaks were similar between academic and community centers, survival rates were higher in patients treated in an academic setting.

Life Sciences & Biomedicine

Otorhinolaryngology

Science & Technology

Surgery

Details

Title: Subtitle: The Effect of Treating Institution on Outcomes in Head and Neck Cancer
Creators: Amy Anne D. Lassig - University of Minnesota
Anne M. Joseph - University of Minnesota
Bruce R. Lindgren - University of Minnesota
Patricia Fernandes - University of Minnesota
Sarah Cooper - University of Minnesota
Chelsea Schotzko - University of Minnesota
Samir Khariwala - University of Minnesota
Margaret Reynolds - University of Minnesota
Bevan Yueh - University of Minnesota
Resource Type: Journal article
Publication Details: Otolaryngology-head and neck surgery, Vol.147(6), pp.1083-1092
DOI: 10.1177/0194599812457324
PMID: 22875780
PMCID: PMC5552409
NLM abbreviation: Otolaryngol Head Neck Surg
ISSN: 0194-5998
eISSN: 1097-6817
Publisher: Sage
Number of pages: 10
Grant note: KL2TR000113 / NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS) American Academy of Otolaryngology-Head and Neck Surgery Rande H. Lazar Health Services Research Grant
Language: English
Date published: 12/2012
Academic Unit: Otolaryngology
Record Identifier: 9984966747402771

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