The Effects of Intravenous Lidocaine Infusions on the Quality of Recovery and Chronic Pain After Robotic Thyroidectomy: A Randomized, Double-Blinded, Controlled Study

Kwan Woong Choi; Kee-Hyun Nam; Jeong-Rim Lee; Woong Youn Chung; Sang-Wook Kang; Young Eun Joe; Jae Hoon Lee

doi:10.1007/s00268-016-3842-1

Back

The Effects of Intravenous Lidocaine Infusions on the Quality of Recovery and Chronic Pain After Robotic Thyroidectomy: A Randomized, Double-Blinded, Controlled Study

Journal article

Peer reviewed

The Effects of Intravenous Lidocaine Infusions on the Quality of Recovery and Chronic Pain After Robotic Thyroidectomy: A Randomized, Double-Blinded, Controlled Study

Kwan Woong Choi, Kee-Hyun Nam, Jeong-Rim Lee, Woong Youn Chung, Sang-Wook Kang, Young Eun Joe and Jae Hoon Lee

World journal of surgery, Vol.41(5), pp.1305-1312

05/01/2017

DOI: 10.1007/s00268-016-3842-1

PMID: 27896411

Files and links (1)

url

https://link.springer.com/article/10.1007%2Fs00268-016-3842-1View

Open Access

Abstract

Background The effect of the systemic lidocaine on postoperative recovery has not been definitively investigated despite its analgesic efficacy after surgery. The aim of this randomized, double-blinded, controlled study was to evaluate the effect of intravenously administered lidocaine on the quality of recovery and on acute and chronic postoperative pain after robot-assisted thyroidectomy. Methods Ninety patients who were undergoing robotic thyroidectomy were randomly assigned to the lidocaine or the control groups. The patients received 2 mg/kg of lidocaine followed by continuous infusions of 3 mg/kg/h of lidocaine (Group L) or the same volume of 0.9% normal saline (Group C) intravenously during anesthesia. The acute pain profiles and the quality of recovery, which was assessed using the quality of recovery-40 questionnaire (QoR-40), were evaluated for 2 days postoperatively. Chronic postsurgical pain (CPSP) and sensory disturbances at the surgical sites were evaluated 3 months after surgery. Results The QoR-40 and pain scores that were assessed during the 2 days that followed surgery were largely comparable between the groups. However, CPSP was more prevalent in the Group C than in the Group L (16/43 vs. 6/41; p = 0.025). The tactile sensory score 3 months after the operation was significantly greater in the Group L than in the Group C (7 vs. 5; p = 0.001). Conclusion Systemic lidocaine administration was associated with reductions in CPSP and sensory impairment after robot-assisted thyroidectomy although it was not able to reduce acute postsurgical pain or improve the quality of recovery.

Life Sciences & Biomedicine

Science & Technology

Surgery

Details

Title: Subtitle: The Effects of Intravenous Lidocaine Infusions on the Quality of Recovery and Chronic Pain After Robotic Thyroidectomy: A Randomized, Double-Blinded, Controlled Study
Creators: Kwan Woong Choi - Ilsan Hosp, Dept Anesthesiol & Pain Med, Natl Hlth Insurance Serv, Goyang, South Korea
Kee-Hyun Nam - Yonsei University
Jeong-Rim Lee - Yonsei University
Woong Youn Chung - Yonsei University
Sang-Wook Kang - Yonsei University
Young Eun Joe - Yonsei University
Jae Hoon Lee - Yonsei University
Resource Type: Journal article
Publication Details: World journal of surgery, Vol.41(5), pp.1305-1312
DOI: 10.1007/s00268-016-3842-1
PMID: 27896411
NLM abbreviation: World J Surg
ISSN: 0364-2313
eISSN: 1432-2323
Publisher: Springer Nature
Number of pages: 8
Grant note: NRF-2014R1A1A1002001 / Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT and Future Planning
Language: English
Date published: 05/01/2017
Academic Unit: Anesthesia
Record Identifier: 9984806508002771

Metrics

3 Record Views

32 Times Cited - Web of Science