Journal article
The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD) and the European Federation for Colposcopy (EFC) consensus statements on pre-invasive vulvar lesions
International journal of gynecological cancer, Vol.32(7), pp.830-845
06/21/2022
DOI: 10.1136/ijgc-2021-003262
PMCID: PMC9279839
PMID: 35728950
Abstract
The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD), and the European Federation for Colposcopy (EFC) developed consensus statements on pre-invasive vulvar lesions in order to improve the quality of care for patients with vulvar squamous intraepithelial neoplasia, vulvar Paget disease in situ, and melanoma in situ. For differentiated vulvar intraepithelial neoplasia (dVIN), an excisional procedure must always be adopted. For vulvar high-grade squamous intraepithelial lesion (VHSIL), both excisional procedures and ablative ones can be used. The latter can be considered for anatomy and function preservation and must be preceded by several representative biopsies to exclude malignancy. Medical treatment (imiquimod or cidofovir) can be considered for VHSIL. Recent studies favor an approach of using imiquimod in vulvar Paget’s disease. Surgery must take into consideration that the extension of the disease is usually wider than what is evident in the skin. A 2 cm margin is usually considered necessary. A wide local excision with 1 cm free surgical margins is recommended for melanoma in situ. Following treatment of pre-invasive vulvar lesions, women should be seen on a regular basis for careful clinical assessment, including biopsy of any suspicious area. Follow-up should be modulated according to the risk of recurrence (type of lesion, patient age and immunological conditions, other associated lower genital tract lesions).
Details
- Title: Subtitle
- The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD) and the European Federation for Colposcopy (EFC) consensus statements on pre-invasive vulvar lesions
- Creators
- Mario Preti - University of TurinElmar Joura - Medical University of ViennaPedro Vieira-Baptista - Lower Genital Tract Unit, Centro Hospitalar de São João, Porto, PortugalMarc Van Beurden - Centre for Gynecological Oncology Amsterdam, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The NetherlandsFederica Bevilacqua - Department of Surgical Sciences, University of Torino, Torino, ItalyMaaike C G Bleeker - Department of Pathology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, NetherlandsJacob Bornstein - Galilee Medical Center and Azrieli Faculty of Medicine, Bar-Ilan, IsraelXavier Carcopino - Department of Obstetrics and Gynaecology, Hôpital Nord, APHM, Aix-Marseille University (AMU), Univ Avignon, CNRS, IRD, IMBE UMR 7263, 13397, Marseille, FranceCyrus Chargari - Department of Radiation Oncology, Gustave Roussy Cancer Campus, Paris, FranceMargaret E Cruickshank - Aberdeen Centre for Women’s Health Research, University of Aberdeen, Aberdeen, UKBilal Emre Erzeneoglu - Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynaecological Oncology, Hacettepe University, Ankara, TurkeyNiccolò Gallio - Department of Surgical Sciences, University of Torino, Torino, ItalyDebra Heller - Rutgers New Jersey Medical School, Newark, New Jersey, USAVesna Kesic - Department of Obstetrics and Gynecology, University of Belgrade, Belgrade, SerbiaOlaf Reich - Department of Obstetrics and Gynecology, Medical University of Graz, Graz, AustriaColleen K Stockdale - Department of Obstetrics & Gynecology, University of Iowa, Iowa City, Iowa, USABilal Esat Temiz - Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynaecological Oncology, Hacettepe University, Ankara, TurkeyLinn Woelber - Dysplasia Center Hamburg, Jerusalem Hospital, Hamburg, GermanyFrançois Planchamp - Clinical Research Unit, Institut Bergonie, Bordeaux, FranceJana Zodzika - Department of Obstetrics and Gynaecology Rīga Stradiņš university, Riga, LatviaDenis Querleu - Division of Gynecologic Oncology, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, ItalyMurat Gultekin - Division of Gynaecological Oncology, Department of Obstetrics and Gynaecology, Hacettepe University Faculty of Medicine, Ankara, Turkey
- Resource Type
- Journal article
- Publication Details
- International journal of gynecological cancer, Vol.32(7), pp.830-845
- Publisher
- BMJ Publishing Group Ltd
- DOI
- 10.1136/ijgc-2021-003262
- PMID
- 35728950
- PMCID
- PMC9279839
- ISSN
- 1048-891X
- eISSN
- 1525-1438
- Language
- English
- Date published
- 06/21/2022
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9984318225102771
Metrics
15 Record Views