Journal article
The Importance of Timing in Optimizing Cranial Vault Remodeling in Syndromic Craniosynostosis
Plastic and reconstructive surgery (1963), Vol.135(4), pp.1077-1084
04/2015
DOI: 10.1097/PRS.0000000000001058
PMID: 25502856
Abstract
BACKGROUND:The purpose of this study was to gain insight into the impact of age at repair on relapse rates in syndromic patients undergoing cranial vault remodeling.
METHODS:Retrospective chart review was performed for patients surgically treated for syndromic craniosynostosis from 1990 to 2013. Surgical procedures were assigned a Whitaker category based on need for reoperation as followsno additional surgery required (category I); minor contouring revisions required (II); major revisions required (III); or failure of original surgery (IV). Age at surgery was grouped as followsyounger than 6 months; aged 6 to 9 months; and older than 9 months. Multivariable logistic regression analysis was performed to determine the relationship between age at surgery and need for reoperation by Whitaker category.
RESULTS:Fifty-two patients undergoing a total of 65 planned cranial vault remodeling procedures were included. Multivariate logistic regression analysis revealed that patients younger than 6 months at the time of primary surgery carried a 4.10 greater odds (95 percent CI, 1.31 to 12.87; p = 0.016) of requiring a subsequent major reoperation, and being older than 9 months of age carried a 13.2 greater odds (95 percent CI, 1.39 to 124.30; p = 0.024) of requiring a subsequent minor revision.
CONCLUSIONS:Timing of surgery is an important factor to consider when planning vault remodeling in syndromic craniosynostosis. Based on our institution’s experience, when there is no concern for elevated intracranial pressure the ideal operative window for these procedures in the syndromic population appears to be 6 to 9 months of age.
CLINICAL QUESTION/LEVEL OF EVIDENCE:Risk, II.
Details
- Title: Subtitle
- The Importance of Timing in Optimizing Cranial Vault Remodeling in Syndromic Craniosynostosis
- Creators
- Alan Utria - Johns Hopkins HospitalGerhard Mundinger - Johns Hopkins HospitalJustin Bellamy - Johns Hopkins HospitalJoy Zhou - Johns Hopkins HospitalAli Ghasemzadeh - American Cleft Palate-Craniofacial AssociationRobin Yang - University of Maryland Medical CenterGeorge Jallo - Johns Hopkins HospitalEdward Ahn - University of Maryland Medical CenterAmir Dorafshar - Johns Hopkins Hospital
- Resource Type
- Journal article
- Publication Details
- Plastic and reconstructive surgery (1963), Vol.135(4), pp.1077-1084
- DOI
- 10.1097/PRS.0000000000001058
- PMID
- 25502856
- NLM abbreviation
- Plast Reconstr Surg
- ISSN
- 0032-1052
- eISSN
- 1529-4242
- Publisher
- American Society of Plastic Surgeons
- Number of pages
- 8
- Language
- English
- Date published
- 04/2015
- Academic Unit
- Surgery
- Record Identifier
- 9985015820902771
Metrics
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