Journal article
The Influence of Continuous Epidural Bupivacaine Analgesia on the Second Stage of Labor and Method of Delivery in Nulliparous Women
Anesthesiology (Philadelphia), Vol.66(6), pp.774-780
06/1987
DOI: 10.1097/00000542-198706000-00011
PMID: 3296856
Abstract
A randomized, double blind, placebo-controlled study was performed to evaluate the analgesic efficacy and influence of continuing an epidural infusion of 0.125% bupivacaine beyond a cervical dilatation of 8 cm in nulliparous women. When the cervix was greater than or equal to 8 cm dilated, coded study solution was substituted for the known 0.125% bupivacaine solution. The study solution for 46 patients was 0.125% bupivacaine; 46 patients received saline. During the first stage of labor, 44 (96%) women in the bupivacaine group, and 45 (98%) in the saline group, had analgesia of excellent or good quality. During the second stage, 36 (82%) women in the bupivacaine group, versus 18 (41%) women in the saline group, had analgesia of excellent or good quality (P less than .0001). Six (13%) women in each group underwent cesarean delivery after the start of the study solution. Among the women who delivered vaginally, the mean (+/- S.D.) duration of the second stage of labor was 124 (+/- 70) min in the bupivacaine group, versus 94 (+/- 54) min in the saline group (P less than .05). Twenty-one of 40 (53%) women in the bupivacaine group, versus 11 of 40 (28%) in the saline group, underwent instrumental vaginal delivery (P less than .05). Twenty-eight of 40 (70%) women in the bupivacaine group, versus six of 40 (15%) in the saline group; had surgical perineal anesthesia for vaginal delivery (P less than .0001). There were no significant differences between groups in Apgar scores or umbilical cord blood acid-base values.(ABSTRACT TRUNCATED AT 250 WORDS)
Details
- Title: Subtitle
- The Influence of Continuous Epidural Bupivacaine Analgesia on the Second Stage of Labor and Method of Delivery in Nulliparous Women
- Creators
- David H ChestnutGail E VandewalkerCindy L OwenJames N BatesWon W Chol
- Resource Type
- Journal article
- Publication Details
- Anesthesiology (Philadelphia), Vol.66(6), pp.774-780
- DOI
- 10.1097/00000542-198706000-00011
- PMID
- 3296856
- NLM abbreviation
- Anesthesiology
- ISSN
- 0003-3022
- eISSN
- 1528-1175
- Language
- English
- Date published
- 06/1987
- Academic Unit
- Anesthesia
- Record Identifier
- 9984006411302771
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