Journal article
The Iowa multiplex family study of schizophrenia: Linkage analyses on chromosome 5
European Archives of Psychiatry and Neurological Sciences, Vol.239(5), pp.290-292
09/1990
DOI: 10.1007/BF01735053
PMID: 2140777
Abstract
We analysed six multiplex pedigrees of schizophrenia for linkage to two DNA probes mapping to the chromosome 5q11–q13 region where linkage to a gene for schizophrenia was recently reported. Analyses were conducted using three penetrance models and considering the affected state to be schizophrenia, the schizophrenia spectrum, and all psychiatric diagnoses. All analyses gave consistently negative lod scores. Although the region was not formally excluded, no evidence for linkage was found.
Details
- Title: Subtitle
- The Iowa multiplex family study of schizophrenia: Linkage analyses on chromosome 5
- Creators
- Raymond R CroweDonald W BlackNancy C AndreasenMichael Huether
- Resource Type
- Journal article
- Publication Details
- European Archives of Psychiatry and Neurological Sciences, Vol.239(5), pp.290-292
- DOI
- 10.1007/BF01735053
- PMID
- 2140777
- ISSN
- 0175-758X
- eISSN
- 1433-8491
- Language
- English
- Date published
- 09/1990
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003447202771
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