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The Landmark Series: Management of Small Bowel Neuroendocrine Tumors
Journal article   Peer reviewed

The Landmark Series: Management of Small Bowel Neuroendocrine Tumors

Catherine G Tran, Scott K Sherman and James R Howe
Annals of surgical oncology, Vol.28(5), pp.2741-2751
05/2021
DOI: 10.1245/s10434-020-09566-4
PMCID: PMC8604156
PMID: 33452604

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Abstract

Surgical resection is the foundation for treatment of small bowel neuroendocrine tumors (SBNETs). Guidelines for surgical management of SBNETs rely on retrospective data, which suggest that primary tumor resection and cytoreduction improve symptoms, prevent future complications, and lengthen survival. In advanced NETs, improvement in progression-free survival has been reported in large, randomized, controlled trials of various medical treatments, including somatostatin analogues, targeted therapy, and peptide receptor radionuclide therapy. This review discusses important studies influencing the management of SBNETs and the limitations of current evidence regarding surgical interventions for SBNETs.
Humans Intestinal Neoplasms - therapy Intestine, Small Neuroendocrine Tumors - therapy Pancreatic Neoplasms Retrospective Studies

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