Journal article
The Modern Metabolic Stone Evaluation in Children
Urology (Ridgewood, N.J.), Vol.101, pp.15-20
03/2017
DOI: 10.1016/j.urology.2016.09.058
PMID: 27838366
Abstract
To evaluate metabolic abnormalities in a contemporary pediatric population after their first stone episode. The incidence of pediatric nephrolithiasis is increasing and therefore the etiologies contributing to today's pediatric stone formation may also be changing.
A retrospective review of all consecutive children presenting after their first kidney stone between 2000 and 2014 was performed. We compared demographic data, serum chemistry results, and 24-hour urine results and treatments.
One hundred thirteen children with a mean age of 11 years (5 months to 18 years) who presented with their first kidney stone episode between 2000 and 2014 were evaluated. Sixteen patients (14%) were found to have an underlying genetic or systemic disease. Overall, there was a low rate of serum chemistry abnormalities. The most common abnormalities found within the 24-hour urine evaluation included low urine volume (89%) and hypocitraturia (68%). Hypercalciuria occurred rarely (11%).
We identified a low rate of underlying genetic or systemic diseases contributing to modern pediatric stone presentation and an increased proportion of idiopathic stones. Our study differs from historical findings by identifying a low rate of hypercalciuria and a high rate of low urine volume and hypocitraturia, suggestive of changing metabolic abnormalities contributing to modern pediatric stone disease.
Details
- Title: Subtitle
- The Modern Metabolic Stone Evaluation in Children
- Creators
- Mark Bevill - Department of Urology, University of Iowa, Iowa City, IAAmbika Kattula - Department of Urology, University of Iowa, Iowa City, IAChristopher S Cooper - Department of Urology, University of Iowa, Iowa City, IADouglas W Storm - Department of Urology, University of Iowa, Iowa City, IA. Electronic address: douglas-storm@uiowa.edu
- Resource Type
- Journal article
- Publication Details
- Urology (Ridgewood, N.J.), Vol.101, pp.15-20
- Publisher
- United States
- DOI
- 10.1016/j.urology.2016.09.058
- PMID
- 27838366
- ISSN
- 0090-4295
- eISSN
- 1527-9995
- Language
- English
- Date published
- 03/2017
- Academic Unit
- Stead Family Department of Pediatrics; Urology; Medicine Administration
- Record Identifier
- 9984051784202771
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