Journal article
The Mystery of Candida albicans Hyphal Morphogenesis in the Macrophage Phagolysosome
Infection and immunity, Vol.91(5), e0010423
05/2023
DOI: 10.1128/iai.00104-23
PMCID: PMC10187117
PMID: 37129514
Abstract
C. albicans transitions between budding yeast and filamentous hyphal forms in a process that is tightly associated with its virulence. This transition also occurs after the fungus has been phagocytosed by macrophages. A number of somewhat discordant models have been proposed for the environmental characteristics of the phagolysosome that induce this transition. H. B. Wilson and M. C. Lorenz (Infect Immun 91:e00087-23, 2023, https://doi.org/10.1128/iai.00087-23) revisited these models and found that none of them explained morphogenesis in the macrophage.
Details
- Title: Subtitle
- The Mystery of Candida albicans Hyphal Morphogenesis in the Macrophage Phagolysosome
- Creators
- Damian J. Krysan - University of Iowa
- Contributors
- Mairi C. Noverr (Editor)
- Resource Type
- Journal article
- Publication Details
- Infection and immunity, Vol.91(5), e0010423
- Publisher
- American Society for Microbiology
- DOI
- 10.1128/iai.00104-23
- PMID
- 37129514
- PMCID
- PMC10187117
- ISSN
- 0019-9567
- eISSN
- 1098-5522
- Number of pages
- 3
- Grant note
- 1R01AI133409 / HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) (https://doi.org/10.13039/100000060)
- Language
- English
- Electronic publication date
- 04/27/2023
- Date published
- 05/2023
- Academic Unit
- Molecular Physiology and Biophysics; Microbiology and Immunology; Stead Family Department of Pediatrics; Infectious Disease (Pediatrics)
- Record Identifier
- 9984399497802771
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