Journal article
The NIH Extracellular RNA Communication Consortium
Journal of extracellular vesicles, Vol.4(1), pp.27493-n/a
01/01/2015
DOI: 10.3402/jev.v4.27493
PMCID: PMC4553264
PMID: 26320938
Abstract
The Extracellular RNA (exRNA) Communication Consortium, funded as an initiative of the NIH Common Fund, represents a consortium of investigators assembled to address the critical issues in the exRNA research arena. The overarching goal is to generate a multi-component community resource for sharing fundamental scientific discoveries, protocols, and innovative tools and technologies. The key initiatives include (a) generating a reference catalogue of exRNAs present in body fluids of normal healthy individuals that would facilitate disease diagnosis and therapies, (b) defining the fundamental principles of exRNA biogenesis, distribution, uptake, and function, as well as development of molecular tools, technologies, and imaging modalities to enable these studies, (c) identifying exRNA biomarkers of disease, (d) demonstrating clinical utility of exRNAs as therapeutic agents and developing scalable technologies required for these studies, and (e) developing a community resource, the exRNA Atlas, to provide the scientific community access to exRNA data, standardized exRNA protocols, and other useful tools and technologies generated by funded investigators.
Details
- Title: Subtitle
- The NIH Extracellular RNA Communication Consortium
- Creators
- Alexandra M. Ainsztein - National Institute of General Medical SciencesPhilip J. Brooks - National Center for Advancing Translational SciencesVivien G. Dugan - National Institute of Allergy and Infectious DiseasesAniruddha Ganguly - Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute (NCI), Rockville, MD, USA.Max Guo - National Institute on AgingT. Kevin Howcroft - Division of Cancer Biology Cancer Immunology, Hematology, and Etiology Branch, National Cancer Institute (NCI), Rockville, MD, USAChristine A. Kelley - National Institute of Biomedical Imaging and BioengineeringLillian S. Kuo - National Center for Advancing Translational SciencesPatricia A. Labosky - Division of Program Coordination Planning and Strategic InitiativesRebecca Lenzi - Division of Program Coordination Planning and Strategic InitiativesGeorge A. Mckie - National Eye InstituteSuresh Mohla - National Cancer InstituteDena Procaccini - National Institute on Drug AbuseMatthew Reilly - National Institute on Alcohol Abuse and AlcoholismJohn S. Satterlee - National Institute on Drug AbusePothur R. Srinivas - National Heart Lung and Blood InstituteElizabeth Stansell Church - National Institute of Allergy and Infectious DiseasesMargaret Sutherland - National Institute of Neurological Disorders and StrokeDanilo A. Tagle - National Center for Advancing Translational SciencesJessica M. Tucker - National Institute of Biomedical Imaging and BioengineeringSundar Venkatachalam - National Institute of Dental and Craniofacial Research
- Resource Type
- Journal article
- Publication Details
- Journal of extracellular vesicles, Vol.4(1), pp.27493-n/a
- DOI
- 10.3402/jev.v4.27493
- PMID
- 26320938
- PMCID
- PMC4553264
- NLM abbreviation
- J Extracell Vesicles
- ISSN
- 2001-3078
- eISSN
- 2001-3078
- Publisher
- Taylor & Francis
- Number of pages
- 6
- Language
- English
- Date published
- 01/01/2015
- Academic Unit
- Microbiology and Immunology
- Record Identifier
- 9984297321302771
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