The National Birth Defects Prevention Study: A review of the methods

Jennita Reefhuis; Suzanne M Gilboa; Marlene Anderka; Marilyn L Browne; Marcia L Feldkamp; Charlotte A Hobbs; Mary M Jenkins; Peter H Langlois; Kimberly B Newsome; Andrew F Olshan; Paul A Romitti; Stuart K Shapira; Gary M Shaw; Sarah C Tinker; Margaret A Honein; National Birth Defects Prevention Study

doi:10.1002/bdra.23384

Back

The National Birth Defects Prevention Study: A review of the methods

Journal article

Peer reviewed

The National Birth Defects Prevention Study: A review of the methods

Jennita Reefhuis, Suzanne M Gilboa, Marlene Anderka, Marilyn L Browne, Marcia L Feldkamp, Charlotte A Hobbs, Mary M Jenkins, Peter H Langlois, Kimberly B Newsome, Andrew F Olshan, …

Birth defects research. A Clinical and molecular teratology, Vol.103(8), pp.656-669

08/2015

DOI: 10.1002/bdra.23384

PMCID: PMC4558899

PMID: 26033852

Files and links (1)

url

https://www.ncbi.nlm.nih.gov/pmc/articles/4558899View

Open Access

Abstract

The National Birth Defects Prevention Study (NBDPS) is a large population-based multicenter case-control study of major birth defects in the United States. Data collection took place from 1998 through 2013 on pregnancies ending between October 1997 and December 2011. Cases could be live born, stillborn, or induced terminations, and were identified from birth defects surveillance programs in Arkansas, California, Georgia, Iowa, Massachusetts, New Jersey, New York, North Carolina, Texas, and Utah. Controls were live born infants without major birth defects identified from the same geographical regions and time periods as cases by means of either vital records or birth hospitals. Computer-assisted telephone interviews were completed with women between 6 weeks and 24 months after the estimated date of delivery. After completion of interviews, families received buccal cell collection kits for the mother, father, and infant (if living). There were 47,832 eligible cases and 18,272 eligible controls. Among these, 32,187 (67%) and 11,814 (65%), respectively, provided interview information about their pregnancies. Buccal cell collection kits with a cytobrush for at least one family member were returned by 19,065 case and 6,211 control families (65% and 59% of those who were sent a kit). More than 500 projects have been proposed by the collaborators and over 200 manuscripts published using data from the NBDPS through December 2014. The NBDPS has made substantial contributions to the field of birth defects epidemiology through its rigorous design, including case classification, detailed questionnaire and specimen collection, large study population, and collaborative activities across Centers.

Genetic Markers

United States - epidemiology

Congenital Abnormalities - epidemiology

Genetic Predisposition to Disease

Congenital Abnormalities - prevention & control

Humans

Female

Neonatal Screening - methods

Data Collection - methods

Infant, Newborn

Population Surveillance - methods

Details

Title: Subtitle: The National Birth Defects Prevention Study: A review of the methods
Creators: Jennita Reefhuis - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia
Suzanne M Gilboa - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia
Marlene Anderka - Massachusetts Department of Public Health, Boston, Massachusetts
Marilyn L Browne - University at Albany School of Public Health, Rensselaer, New York
Marcia L Feldkamp - University of Utah School of Medicine, Salt Lake City, Utah
Charlotte A Hobbs - College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas
Mary M Jenkins - Centers for Disease Control and Prevention
Peter H Langlois - Texas Department of State Health Services, Austin, Texas
Kimberly B Newsome - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia
Andrew F Olshan - University of North Carolina, Chapel Hill, North Carolina
Paul A Romitti - University of Iowa, Iowa City, Iowa
Stuart K Shapira - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia
Gary M Shaw - Stanford University School of Medicine, Stanford, California
Sarah C Tinker - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia
Margaret A Honein - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia
National Birth Defects Prevention Study
Resource Type: Journal article
Publication Details: Birth defects research. A Clinical and molecular teratology, Vol.103(8), pp.656-669
DOI: 10.1002/bdra.23384
PMID: 26033852
PMCID: PMC4558899
NLM abbreviation: Birth Defects Res A Clin Mol Teratol
ISSN: 1542-0752
eISSN: 1542-0760
Publisher: United States
Grant note: P2C HD050924 / NICHD NIH HHS DK56350 / NIDDK NIH HHS P30 DK056350 / NIDDK NIH HHS CC999999 / Intramural CDC HHS U01 DD001035 / NCBDD CDC HHS
Language: English
Date published: 08/2015
Academic Unit: Epidemiology; Biostatistics
Record Identifier: 9983995063102771

Metrics

27 Record Views

201 Times Cited - Web of Science