Journal article
The Neuropsychology of the Prefrontal Cortex
Archives of neurology (Chicago), Vol.50(6), pp.636-642
06/01/1993
DOI: 10.1001/archneur.1993.00540060066020
PMID: 8503801
Abstract
• Single photon emission computed tomography with the xenon inhalation technique is used to compare activation of regional cerebral blood flow in frontal brain regions during the performance of four widely used neuropsychological tests: the Continuous Performance Test, the Wisconsin Card Sorting Test, the Tower of London, and Porteus Mazes. Healthy normal volunteers performing these tasks show significant increases in frontal regions during the Continuous Performance Test, the Wisconsin Card Sorting Test, and the Tower of London, but not the Porteus Mazes. Activation produced by the Continuous Performance Test and the Tower of London are mesial and bilateral and may reflect stimulation of midline attentional circuits. The Wisconsin Card Sorting Test produces a left dorsolateral area of prefrontal activation. These findings indicate that regional activation of the frontal lobes occurs in response to cognitive challenges produced through performance of standard neuropsychological tests.
Details
- Title: Subtitle
- The Neuropsychology of the Prefrontal Cortex
- Creators
- Karim RezaiNancy C AndreasenRandy AlligerGregg CohenVictor SwayzeDaniel S O'Leary
- Resource Type
- Journal article
- Publication Details
- Archives of neurology (Chicago), Vol.50(6), pp.636-642
- DOI
- 10.1001/archneur.1993.00540060066020
- PMID
- 8503801
- NLM abbreviation
- Arch Neurol
- ISSN
- 0003-9942
- eISSN
- 1538-3687
- Publisher
- American Medical Association
- Language
- English
- Date published
- 06/01/1993
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003908702771
Metrics
23 Record Views