Journal article
The Nitinol Vascular Occlusion Plug: Preliminary Experimental Evaluation in Peripheral Veins
Journal of vascular and interventional radiology, Vol.10(1), pp.23-27
1999
DOI: 10.1016/S1051-0443(99)70004-7
PMID: 10872485
Abstract
To compare the nitinol occlusion plug with standard stainless steel coils for the occlusion of moderate-size peripheral veins.
The nitinol plug is a braided multilayered vascular occlusion device filled with thrombogenic polyester fibers. It is self-expanding and can be recaptured into its 6-F introducing sheath for repositioning prior to detachment. Ten occlusion procedures were performed in five dogs from a retrograde transjugular venous approach. Five nitinol plugs (diameter: 7.4 mm ± 0.5) were deployed in five femoropopliteal veins (diameter: 6.5 mm ± 0.7; mean oversizing 14.6%). Two sequential Gianturco coils (diameter: 7.4 mm ± 0.9) were deployed in the corresponding contralateral veins (diameter: 6.2 mm ± 0.8; mean oversizing 19.6%). Follow-up venography was performed at 1 month, following which the animals were killed and the vessels were explanted.
Time-to-occlusion was significantly shorter with the nitinol plug as compared to two Gianturco coils (4.2 minutes ± 3.4 vs 25.6 minutes ± 14.1, respectively P < .03]). At 1 month all but one coil-doublet (80%) had recanalized or migrated, compared to only one nitinol occluder (20%, P < .04). Histopathologic examination of plug-occluded veins showed a uniform organized matrix and underlying intimal proliferative response.
A single nitinol occluder resulted in significantly faster occlusion time and significantly lower recanalization or migration rate than two Gianturco coils, in moderate-size peripheral veins.
Details
- Title: Subtitle
- The Nitinol Vascular Occlusion Plug: Preliminary Experimental Evaluation in Peripheral Veins
- Creators
- Melhem J.A SharafuddinXiaoping GuMyra UrnessKurt Amplatz
- Resource Type
- Journal article
- Publication Details
- Journal of vascular and interventional radiology, Vol.10(1), pp.23-27
- Publisher
- Elsevier Inc
- DOI
- 10.1016/S1051-0443(99)70004-7
- PMID
- 10872485
- ISSN
- 1051-0443
- eISSN
- 1535-7732
- Language
- English
- Date published
- 1999
- Academic Unit
- Radiology; Surgery
- Record Identifier
- 9984051718502771
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