The Open Molecular Software Foundation (OMSF) and the Growing Role of Open Source Software in Molecular Modeling

The authors thank all contributors and advisors to the OMSF ecosystem, who are too many to mention. The work described in this Perspective was made possible by financial and in-kind contributions from our current and past industrial partners-the list of partners for each consortium can be found on the project websites (openforcefield.org, openfree.energy, openfold.io, and openadmet.org). This effort also benefited significantly from strategic grant funding. The OpenFF Initiative appreciates support from the National Institutes of Health (R01GM132386). J.K.L. acknowledges funding from the National Science Foundation (NSF) (POSE Grant NSF-TI 2346068) and the Rosetta Commons. K.C.-J. acknowledges support from NSF (POSE Grant TI-2303740) and the Chan Zuckerberg Initiative (CZI EOSS5 2022-252547) for our ecosystem-building initiatives. Finally, OpenADMET research reported in this publication was supported by the Advanced Research Projects Agency for Health (ARPA-H) under "AVOID-OME: Structurally enabling the "avoid-ome" to accelerate drug discovery" and Award 1AY1AX000035-01. The ARPA-H award provided 80% of total costs and a total of $3,739,838.00. The content is solely the responsibility of the authors and does not necessarily represent the official views of the U.S. Department of Health and Human Services, ARPA-H, or the U.S. Government.