The Patient Typology about deprescribing and medication-related decisions: A quantitative exploration

Kristie Rebecca Weir; Aaron M Scherer; Sarah E Vordenberg; Sven Streit; Jesse Jansen; Katharina Tabea Jungo

doi:10.1111/bcpt.13911

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The Patient Typology about deprescribing and medication-related decisions: A quantitative exploration

Journal article

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The Patient Typology about deprescribing and medication-related decisions: A quantitative exploration

Kristie Rebecca Weir, Aaron M Scherer, Sarah E Vordenberg, Sven Streit, Jesse Jansen and Katharina Tabea Jungo

Basic & clinical pharmacology & toxicology, Vol.134(1), pp.39-50

01/2024

DOI: 10.1111/bcpt.13911

PMCID: PMC11187678

PMID: 37300477

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Abstract

This study aimed to test the adequacy of a quantitative measure of our qualitatively-developed Patient Typology - categories of older adults' attitudes towards medicines and medicine decision-making - and identify characteristics associated with each Typology. We conducted secondary data analyses of a subset of survey item measures of adults (≥65 years) who were members of online survey panels in Australia, the UK, the US, and the Netherlands (n=4,688). Multinomial logistic regression analyses assessed associations between demographic, psychosocial, and medication-related measures. Mean age was 71.5 (5) and 47.5% of participants were female. Factors associated with an increased likelihood of identifying with Typology 1 'Attached to medicines' over Typology 2 'Open to deprescribing' were higher positive attitude towards polypharmacy (RRR=1.12, p =<.001) and higher need for certainty (RRR=1.11, p=.039). Factors associated with an increased likelihood of identifying with Typology 3 'Defers (medication decision-making) to others' over Typology 2 were older age (RRR=1.47 per 10-year age increase, p=<.001) and a decreased likelihood of prior deprescribing experience (RRR=0.73, p=.033). This study provides validation of the Typology with large samples from four countries, with the quantitatively-measured typologies generally aligning with the qualitatively-derived categories. Our Patient Typology measure provides a succinct way researchers can assess attitudes towards deprescribing.

older adults

shared decision making

consumer preferences

polypharmacy

Communication

Details

Title: Subtitle: The Patient Typology about deprescribing and medication-related decisions: A quantitative exploration
Creators: Kristie Rebecca Weir - University of Bern
Aaron M Scherer - University of Iowa
Sarah E Vordenberg - University of Michigan
Sven Streit - University of Bern
Jesse Jansen - Maastricht University
Katharina Tabea Jungo - University of Bern
Resource Type: Journal article
Publication Details: Basic & clinical pharmacology & toxicology, Vol.134(1), pp.39-50
DOI: 10.1111/bcpt.13911
PMID: 37300477
PMCID: PMC11187678
NLM abbreviation: Basic Clin Pharmacol Toxicol
eISSN: 1742-7843
Grant note: DOI: 10.13039/100000049, name: National Institute on Aging, award: R24AG064025, 1K01AG065440; DOI: 10.13039/501100001711, name: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, award: P500PM_206728
Language: English
Electronic publication date: 06/10/2023
Date published: 01/2024
Academic Unit: General Internal Medicine; Internal Medicine
Record Identifier: 9984438957002771

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