Journal article
The Perioperative Pain Self-Management (PePS) randomized controlled trial protocol: Preventing chronic post-surgical pain and prolonged opioid use
Contemporary clinical trials, Vol.118, pp.106810-106810
07/2022
DOI: 10.1016/j.cct.2022.106810
PMCID: PMC10498437
PMID: 35660486
Abstract
Total joint arthroplasties are common orthopedic surgeries that carry risk for developing chronic post-surgical pain. In addition to pre- and post-operative pain severity, psychological distress (e.g., anxiety, pain catastrophizing) is a risk factor for chronic postsurgical pain. Cognitive behavioral therapy (CBT) for chronic pain is an empirically supported approach to managing chronic pain, functional impairment, and related distress. While CBT has been used extensively in patients with established chronic pain, using it as a preventive intervention targeting the transition from acute to chronic postsurgical pain is a novel application.
The Perioperative Pain Self-Management (PePS) program is a pain self-management intervention based on the principles of CBT. This innovative intervention is brief, flexible, and is delivered remotely. The current study aims to determine the efficacy of PePS compared to standard care on reducing the incidence of significant surgical site pain at 6-months post-surgery. The current study also aims to evaluate the context for subsequent implementation.
This study is a hybrid type I efficacy-preparing for implementation trial. It is a two-site, single-blind, two-arm, parallel, randomized control trial. Surgical patients will be randomized to either receive: 1) PePS plus standard care, or 2) Standard care. The primary end point will be surgical site pain severity at 6-months post-surgery.
Results from this study are expected to result in support for a brief scalable intervention (PePS) that can prevent the development of chronic pain and prolonged post-surgical opioid use, as well as key details to inform subsequent implementation.
ClinicalTrials.govIdentifier:NCT04979429
Details
- Title: Subtitle
- The Perioperative Pain Self-Management (PePS) randomized controlled trial protocol: Preventing chronic post-surgical pain and prolonged opioid use
- Creators
- Katherine Hadlandsmyth - Iowa City VA Health Care SystemDiana J. Burgess - Center for Care Delivery and Outcomes Research (CCDOR), Minneapolis VA Healthcare System, Minneapolis, MN 55417, USARyan F. Leparski - Iowa City VA Health Care SystemAnnie S. Odom - Iowa City VA Health Care SystemEmily J. Campbell - Center for Care Delivery and Outcomes Research (CCDOR), Minneapolis VA Healthcare System, Minneapolis, MN 55417, USAAshlie A. Obrecht - Iowa City VA Health Care SystemJenna L. Adamowicz - Iowa City VA Health Care SystemHyunkeun Cho - University of IowaKenda Stewart Steffensmeier - Iowa City VA Health Care SystemNicole L. Johnson - Iowa City VA Health Care SystemChristopher C. Richards - Iowa City VA Health Care SystemMark W. Vander Weg - Iowa City VA Health Care SystemBrian C. Lund - Iowa City VA Health Care SystemPatrick Yoon - Center for Care Delivery and Outcomes Research (CCDOR), Minneapolis VA Healthcare System, Minneapolis, MN 55417, USAHilary J. Mosher - Iowa City VA Health Care System
- Resource Type
- Journal article
- Publication Details
- Contemporary clinical trials, Vol.118, pp.106810-106810
- DOI
- 10.1016/j.cct.2022.106810
- PMID
- 35660486
- PMCID
- PMC10498437
- NLM abbreviation
- Contemp Clin Trials
- ISSN
- 1551-7144
- eISSN
- 1559-2030
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 07/2022
- Academic Unit
- Psychiatry; Epidemiology; Psychological and Brain Sciences; Biostatistics; Anesthesia; Injury Prevention Research Center; General Internal Medicine; Community and Behavioral Health; Internal Medicine
- Record Identifier
- 9984267160202771
Metrics
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