Journal article
The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience
Innovations in pharmacy, Vol.13(3), 8
2022
DOI: 10.24926/iip.v13i3.4997
PMCID: PMC9815868
PMID: 36627908
Abstract
Background:
Bacterial antimicrobial resistance (AMR) is a leading cause of mortality worldwide. Although AMR is common in low-income communities, there is limited evidence of the effect of antibiotic stewardship programs in low-income communities in the United States.
Objectives:
Our goal is to assess the effects of implementing pharmacist-led ASP by integrating it with medication therapy management service (MTM) in a low-income serving clinic. We evaluated the following 1) antibiotic prescriptions per 1000 patients, 2) the frequency of clinic (office) visits 30-day post-index clinic visits for recurring infections.
Methods:
To achieve our goal, we conducted a pre-post, quasi-experimental intervention study using an interrupted time-series analysis to assess the following: 1) antibiotic prescriptions per 1000 patients and the 2) frequency of office visits (including telehealth) within 30-day post-index clinic visits associated with recurrent infection.
Results:
Our findings revealed that the long-term effect of our antibiotic stewardship program intervention was associated with 63.69% reduction in antibiotic prescriptions per 1000 patients (change in slope = -0.173, [95% CI: (-0.30, -0.05)], P < 0.007) and a reduction in the frequency of office visits within 30-day post-index clinic visits by 67.27% (change in slope = -2.043, [95% CI: (-3.84, -0.24)], P < 0.028).
Conclusion:
Implementing antibiotic stewardship programs is feasible for clinics serving low-income populations. It was associated with a reduction in antibiotic prescriptions and preventable clinic (office) visits within 30 days due to infection recurrence.
Details
- Title: Subtitle
- The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience
- Creators
- Arinze Nkemdirim Okere - Florida Agricultural and Mechanical UniversityMiquetta L. Trimble - Community Health CenterVassiki Sanogo - Statistical ServiceUkamaka Smith - Florida Agricultural and Mechanical UniversityClyde Brown - Florida Agricultural and Mechanical UniversitySarah G. Buxbaum - Florida Agricultural and Mechanical University
- Resource Type
- Journal article
- Publication Details
- Innovations in pharmacy, Vol.13(3), 8
- DOI
- 10.24926/iip.v13i3.4997
- PMID
- 36627908
- PMCID
- PMC9815868
- NLM abbreviation
- Innov Pharm
- ISSN
- 2155-0417
- eISSN
- 2155-0417
- Publisher
- University of Minnesota Libraries Publishing
- Language
- English
- Date published
- 2022
- Academic Unit
- Pharmacy Practice and Science; Internal Medicine
- Record Identifier
- 9984845053302771
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