Journal article
The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription
Molecular and cellular biology, Vol.9(12), pp.5602-5609
12/1989
DOI: 10.1128/mcb.9.12.5602-5609.1989
PMCID: PMC363730
PMID: 2685570
Abstract
To understand the function of SPT13, a gene encoding a trans-acting factor involved in regulation of Ty-mediated gene expression, we have cloned and sequenced the gene. Our analysis revealed that SPT13 is the same gene as GAL11, a gene in which mutations cause reduced expression of some GAL4-regulated genes. Further analysis of spt13/gal11 mutants suggested that the SPT13 gene also affects transcription of genes involved in mating-type specialization. We show here that SPT13 has both positive and negative regulatory roles in transcription.
Details
- Title: Subtitle
- The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription
- Creators
- Jan S Fassler - Department of Biology, University of Iowa, Iowa City 52242Fred Winston
- Resource Type
- Journal article
- Publication Details
- Molecular and cellular biology, Vol.9(12), pp.5602-5609
- DOI
- 10.1128/mcb.9.12.5602-5609.1989
- PMID
- 2685570
- PMCID
- PMC363730
- ISSN
- 0270-7306
- eISSN
- 1098-5549
- Grant note
- GM32967 / NIGMS NIH HHS GM40306 / NIGMS NIH HHS
- Language
- English
- Date published
- 12/1989
- Academic Unit
- Biology
- Record Identifier
- 9984217534102771
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