The Tadpole Pupil: Case Series With Review of the Literature and New Considerations

Morgane Udry; Randy H Kardon; Federico Sadun; Aki Kawasaki

doi:10.3389/fneur.2019.00846

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The Tadpole Pupil: Case Series With Review of the Literature and New Considerations

Journal article

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The Tadpole Pupil: Case Series With Review of the Literature and New Considerations

Morgane Udry, Randy H Kardon, Federico Sadun and Aki Kawasaki

Frontiers in neurology, Vol.10, 846

08/19/2019

DOI: 10.3389/fneur.2019.00846

PMID: 31481920

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Abstract

Tadpole pupil is a rare phenomenon in which segmental spasm of the iris dilator muscle results in a tadpole-shaped pupil. The pupillary distortion is usually unilateral, lasts several minutes, and can recur in clusters. Any segment of the iris can be affected; thus, for some patients, a different-shaped tadpole pupil is noticed from episode to episode. Tadpole pupil most commonly appears spontaneously in young women. Tadpole pupil is not associated with any systemic disorders, but an ipsilateral Horner syndrome is noted in 46% of patients. In this article, we have reviewed the existing literature of tadpole pupil, compiling all the published cases in a table and reporting four additional cases to re-examine the clinical profile of this disorder and to consider the different purported mechanisms as means to understand its possible etiology and treatment. The common denominator in the pathophysiology of tadpole pupil is a focal excessive contraction (segmental spasm) of the iris dilator muscle. Based on various proposed pathophysiologic mechanism of tadpole pupil, we can consider potential forms of treatment.

Neurology

mydriasis

pupillary distortion

iris dilator muscle

Horner syndrome

pupil

tadpole pupil

Details

Title: Subtitle: The Tadpole Pupil: Case Series With Review of the Literature and New Considerations
Creators: Morgane Udry - FondationAsile des Aveugles, Department of Biology and Medicine, Hôpital Ophtalmique Jules Gonin, University of Lausanne
Randy H Kardon - Department of Ophthalmology and Visual Sciences, Iowa City VA Center of Excellence for the Prevention and Treatment of Vision Loss, University of Iowa and Veterans Affairs Hospital
Federico Sadun - Ospedale Oftalmico Roma, ASL RM1
Aki Kawasaki - FondationAsile des Aveugles, Department of Biology and Medicine, Hôpital Ophtalmique Jules Gonin, University of Lausanne
Resource Type: Journal article
Publication Details: Frontiers in neurology, Vol.10, 846
DOI: 10.3389/fneur.2019.00846
PMID: 31481920
NLM abbreviation: Front Neurol
ISSN: 1664-2295
eISSN: 1664-2295
Publisher: Frontiers Media S.A
Language: English
Date published: 08/19/2019
Academic Unit: Iowa Neuroscience Institute; Ophthalmology and Visual Sciences
Record Identifier: 9984070958902771

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