Journal article
The Toxicology Investigators Consortium Case Registry-the 2021 Annual Report
Journal of medical toxicology, Vol.18(4), pp.267-296
10/01/2022
DOI: 10.1007/s13181-022-00910-6
PMCID: PMC9450833
PMID: 36070069
Abstract
The Toxicology Investigators Consortium (ToxIC) Core Registry was established by the American College of Medical Toxicology in 2010. The Core Registry collects data from participating sites with the agreement that all bedside and telehealth medical toxicology consultations will be entered. This twelfth annual report summarizes the registry's 2021 data and activity with its additional 8552 cases. Cases were identified for inclusion in this report by a query of the ToxIC database for any case entered from January 1 to December 31, 2021. Detailed data was collected from these cases and aggregated to provide information, which included demographics, reason for medical toxicology evaluation, agent and agent class, clinical signs and symptoms, treatments and antidotes administered, mortality, and whether life support was withdrawn. Gender distribution included 50.4% of cases in females, 48.2% of cases in males, and 1.4% of cases in transgender or gender non-conforming individuals. Non-opioid analgesics were the most commonly reported agent class (14.9%), followed by opioids (13.1%). Acetaminophen was the most common agent reported. Fentanyl was the most common opioid reported and was responsible for the greatest number of fatalities. There were 120 fatalities, comprising 1.4% of all cases. Major trends in demographics and exposure characteristics remained similar to past years' reports. Sub-analyses were conducted to describe new demographic characteristics, including marital status, housing status and military service, the continued COVID-19 pandemic and related toxicologic exposures, and novel substances of exposure.
Details
- Title: Subtitle
- The Toxicology Investigators Consortium Case Registry-the 2021 Annual Report
- Creators
- Jennifer S. Love - Icahn School of Medicine at Mount SinaiDana L. Karshenas - American College of Medical ToxicologyMeghan B. Spyres - Phoenix (United States)Lynn A. Farrugia - UF Health Shands HospitalA. Min Kang - Banner - University Medical Center PhoenixHoanVu Nguyen - Washington Poison CenterSharan L. Campleman - American College of Medical ToxicologyShao Li - American College of Medical ToxicologyPaul M. Wax - American College of Medical ToxicologyJeffery Brent - University of Colorado DenverKim Aldy - American College of Medical ToxicologyToxicology Investigators Consortium Study GroupMarielle Brenner (Contributor) - Emergency Medicine
- Resource Type
- Journal article
- Publication Details
- Journal of medical toxicology, Vol.18(4), pp.267-296
- DOI
- 10.1007/s13181-022-00910-6
- PMID
- 36070069
- PMCID
- PMC9450833
- NLM abbreviation
- J Med Toxicol
- ISSN
- 1556-9039
- eISSN
- 1937-6995
- Publisher
- Springer Nature
- Number of pages
- 30
- Grant note
- 1H79TI083343 / American Academy of Addiction Psychiatry 1RO1DA037317-02 / US National Institute of Drug Abuse; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA) BTG International, Inc. (North America) U.S. Food and Drug Administration, Centers for Disease Control and Prevention
- Language
- English
- Date published
- 10/01/2022
- Academic Unit
- Emergency Medicine
- Record Identifier
- 9984656600902771
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