Journal article
The Utility of Magnetic Resonance Imaging in Assessing Patients With Pituitary Tumors Compressing the Anterior Visual Pathway
Journal of neuro-ophthalmology, Vol.37(3), pp.230-238
09/01/2017
DOI: 10.1097/WNO.0000000000000408
PMID: 27391942
Abstract
Background: Pituitary tumors are one of the most common types of intracranial neoplasms, and can cause progressive visual loss. An ongoing challenge in the management of patients with pituitary tumors is the cost, availability, and reliability of current magnetic resonance imaging (MRI) techniques to capture clinically significant incremental tumor growth. The purpose of this study was to evaluate the various MRI-based structural analyses and to explore the relationship between measures of structure and function in the afferent visual pathway of patients with pituitary tumors.
Methods: We performed a critical review of literature on MRI-based structural analyses of pituitary adenomas using PubMed, Embase, Cochrane Library, and Google Scholar. In addition, preoperative structural characteristics of the optic apparatus, optic nerve compression, and optic chiasm elevation identified as important in the literature review, were examined in 18 of our patients from October 2010 to January 2014.
Results: In our review of literature, a total of 443 citations were obtained from our search strategy and review of bibliographies. Eight of these studies met inclusion/exclusion criteria and were retrieved for critical review. Of the 8 included studies, only 2 studies examined the relationship between MRI-based structural measurements and postoperative visual recovery. In our small case-series, MRI analysis of chiasm elevation, severity of optic nerve compression, chiasm position, height of chiasm, tumor height, and tumor volume failed to differentiate patients with postoperative visual dysfunction vs those with visual recovery (P > 0.05).
Conclusions: Although MRI-based structural analysis is an important and useful tool for managing patients with pituitary tumors, there are limited objective measures shown to be predictive of postoperative visual recovery. (C) 2016 by North American Neuro-Ophthalmology Society
Details
- Title: Subtitle
- The Utility of Magnetic Resonance Imaging in Assessing Patients With Pituitary Tumors Compressing the Anterior Visual Pathway
- Creators
- Won Hyung A. Ryu - Univ Calgary, Dept Clin Neurol Sci, Div Neurosurg, Calgary, AB, CanadaYves Starreveld - Univ Calgary, Dept Clin Neurol Sci, Div Neurosurg, Calgary, AB, CanadaJodie M. Burton - Univ Calgary, Dept Clin Neurol Sci, Div Neurol, Calgary, AB, CanadaJunjie LiuFiona Costello - Univ Calgary, Dept Clin Neurol Sci, Div Neurol, Calgary, AB, CanadaPITNET Study Group
- Resource Type
- Journal article
- Publication Details
- Journal of neuro-ophthalmology, Vol.37(3), pp.230-238
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1097/WNO.0000000000000408
- PMID
- 27391942
- ISSN
- 1070-8022
- eISSN
- 1536-5166
- Number of pages
- 9
- Language
- English
- Date published
- 09/01/2017
- Academic Unit
- Neurology
- Record Identifier
- 9984303437802771
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