Journal article
The WASOG Sarcoidosis Organ Assessment Instrument: An update of a previous clinical tool
Sarcoidosis, vasculitis, and diffuse lung diseases, Vol.31(1), pp.19-27
04/18/2014
PMID: 24751450
Abstract
INTRODUCTION A Case Control Etiology of Sarcoidosis Study (ACCESS) sarcoidosis organ assessment instrument has been used for more than a decade to establish uniform standards for the probability of sarcoidosis organ involvement. The ACCESS instrument has become increasingly outdated as new technologies have been developed. Furthermore, the ACCESS instrument failed to address all possible organs involved with sarcoidosis. For these reasons, the World Association of Sarcoidosis and Other Granulomatous Diseases (WASOG) developed a new sarcoidosis organ assessment instrument.METHODSClinical sarcoidosis experts assessed various clinical manifestations for the probability of sarcoidosis organ involvement. Two criteria were required to apply this assessment: 1) histologic evidence of granulomatous inflammation of unknown cause in an organ that was not being assessed; 2) the clinical manifestation being addressed required that alternative causes other than sarcoidosis had been reasonably excluded. Clinical manifestations were assessed as either: a) highly probable: likelihood of sarcoidosis causing this manifestation of at least 90%.; b) probable: likelihood of sarcoidosis causing this manifestation of between 50 and 90%; c) possible: likelihood of sarcoidosis causing this manifestation of less than 50%. The sarcoidosis experts voted on the likelihood of sarcoidosis causing each manifestation using Delphi study methodology where at least 70% agreement of the experts was needed for consensus.RESULTSVarious clinical manifestations were classified as highly probable, at least probable, possible, or indeterminate when no consensus could be reached.CONCLUSIONAn instrument was developed by expert opinion that may be useful for the clinician and researcher in establishing criteria for sarcoidosis organ involvement.
Details
- Title: Subtitle
- The WASOG Sarcoidosis Organ Assessment Instrument: An update of a previous clinical tool
- Creators
- Marc A JudsonUlrich CostabelMarjolein DrentAthol WellsLisa MaierLaura KothHidenobu ShigemitsuDan A CulverJeffrey GelfandDominique ValeyreNadera SweissElliott CrouserAdam S MorgenthauElyse E LowerArata AzumaMami IshiharaShin-Ichiro MorimotoTetsuo YamaguchiNoriharu ShijuboJan C GruttersMisha RosenbachHui-Ping LiPaola RottoliYoshikazu InoueAntje PrasseRobert P BaughmanWASOG Sarcoidosis Organ Assessment Instrument Investigators
- Contributors
- Nabeel Y Hamzeh (Contributor) - University of Iowa, Pulmonary, Critical Care, and Occupational Medicine
- Resource Type
- Journal article
- Publication Details
- Sarcoidosis, vasculitis, and diffuse lung diseases, Vol.31(1), pp.19-27
- PMID
- 24751450
- ISSN
- 1124-0490
- eISSN
- 2532-179X
- Language
- English
- Date published
- 04/18/2014
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
- Record Identifier
- 9984359787502771
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