Journal article
The acute effects of interrupting prolonged sitting with stair climbing on vascular and metabolic function after a high-fat meal
European journal of applied physiology, Vol.120(4), pp.829-839
04/01/2020
DOI: 10.1007/s00421-020-04321-9
PMID: 32065258
Abstract
Purpose Frequent consumption of high-fat meals and prolonged sedentary time are prevalent lifestyles that have been associated with an increased risk of vascular and metabolic complications. This study evaluated the acute effects of interrupting prolonged sitting with stair climbing on vascular and metabolic function after a high-fat meal. Methods In a randomized, cross-over trial, 12 healthy adults (age: 23.5 +/- 2.9 years) consumed a high-fat meal, followed by either 1) a 4-h uninterrupted sitting (sitting trial) or 2) a 4-h sitting interrupted with a 5-min stair climbing (average intensity: 66% of heart rate reserve) every hour (interrupted trial). Plasma triglyceride and glucose concentrations, as well as popliteal artery blood flow and shear rate were assessed at baseline and every hour after a high-fat meal, whereas brachial artery flow-mediated dilation was assessed at baseline and again at the end of each trial. Results Plasma triglyceride and glucose concentrations increased after a high-fat meal and returned to baseline at the end of both trials. Following a high-fat meal, brachial artery flow-mediated dilation decreased in the sitting trial, but not in the interrupted trial (sitting trial: 9.65 +/- 2.63% to 7.84 +/- 2.36%; interrupted trial: 9.41 +/- 2.61% to 10.34 +/- 3.30%, p = 0.009 for interaction). Compared with the sitting trial, the interrupted trial improved popliteal blood flow and shear rate (p = 0.004 and p = 0.008 for interaction, respectively). Conclusions These findings suggest that interrupting prolonged sitting with stair climbing may be an effective lifestyle strategy to prevent against vascular dysfunction that might occur as a result of prolonged sitting after consuming a high-fat meal in young healthy adults.
Details
- Title: Subtitle
- The acute effects of interrupting prolonged sitting with stair climbing on vascular and metabolic function after a high-fat meal
- Creators
- Min Jeong Cho - University of SeoulKanokwan Bunsawat - University of UtahHyun Jeong Kim - University of SeoulEun Sun Yoon - University of SeoulSae Young Jae - University of Seoul
- Resource Type
- Journal article
- Publication Details
- European journal of applied physiology, Vol.120(4), pp.829-839
- DOI
- 10.1007/s00421-020-04321-9
- PMID
- 32065258
- NLM abbreviation
- Eur J Appl Physiol
- ISSN
- 1439-6319
- eISSN
- 1439-6327
- Publisher
- Springer Nature
- Number of pages
- 11
- Grant note
- Ministry of Education of the Republic of Korea; Ministry of Education (MOE), Republic of Korea NRF-2016 S1A 5A2A 03928101 / National Research Foundation of Korea
- Language
- English
- Date published
- 04/01/2020
- Academic Unit
- Health, Sport, and Human Physiology
- Record Identifier
- 9984948145302771
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