Journal article
The association between anxiety disorders and in-hospital outcomes in patients with myocardial infarction
Clinical cardiology (Mahwah, N.J.), Vol.43(6), pp.622-629
06/2020
DOI: 10.1002/clc.23358
PMID: 32187718
Abstract
Background Anxiety disorders are prevalent in patients with myocardial infarction (MI), but the effects of anxiety disorders on in-hospital outcomes within MI patients have not been well studied.
Hypothesis To examine the effects of concurrent anxiety disorders on in-hospital outcomes in MI patients.
Methods We conducted a retrospective cohort study in patients with a principal diagnosis of MI with and without anxiety disorders in the National Inpatient Sample 2016. A total of 129 305 primary hospitalizations for acute MI, 35 237 with ST-segment elevation myocardial infarction (STEMI), and 94 068 with non-ST elevation myocardial infarction (NSTEMI) were identified. Of these, 13 112 (10.1%) had anxiety (7.9% in STEMI and 11.0% in NSTEMI). We compared outcomes of anxiety and nonanxiety groups after propensity score matching for the patient and hospital demographics and relevant comorbidities.
Results After propensity score matching, the anxiety group had a lower incidence of in-hospital mortality (3.0% vs 4.4%, P < .001), cardiac arrest (2.1% vs 2.8%, P < .001), cardiogenic shock (4.9% vs 5.6%, P = .007), and ventricular arrhythmia (6.7% vs 7.9%, P < .001) than the nonanxiety group. In the NSTEMI subgroup, the anxiety group had significantly lower rates of in-hospital mortality (2.3% vs 3.5%, P < .001), cardiac arrest (1.1% vs 1.5%, P = .008), and cardiogenic shock (2.8% vs 3.5%, P = .008). In the STEMI subgroup, we found no differences in in-hospital outcomes (all P > .05) between the matched groups.
Conclusion Although we found that anxiety was associated with better in-hospital outcomes, subgroup analysis revealed that this only applied to patients admitted for NSTEMI instead of STEMI.
Details
- Title: Subtitle
- The association between anxiety disorders and in-hospital outcomes in patients with myocardial infarction
- Creators
- Pengyang Li - Saint Vincent HospitalXiaojia Lu - First Affiliated Hospital of Shantou University Medical CollegeMark Kranis - Saint Vincent HospitalFangcheng Wu - Memorial HospitalCatherine Teng - Greenwich HospitalPeng Cai - Worcester Polytechnic InstituteZeba Hashmath - Saint Vincent HospitalBin Wang - Shantou University
- Resource Type
- Journal article
- Publication Details
- Clinical cardiology (Mahwah, N.J.), Vol.43(6), pp.622-629
- DOI
- 10.1002/clc.23358
- PMID
- 32187718
- ISSN
- 0160-9289
- eISSN
- 1932-8737
- Publisher
- Wiley
- Number of pages
- 8
- Language
- English
- Date published
- 06/2020
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985221242802771
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