Journal article
The association between measures of trochlear morphology and structural features of patellofemoral joint osteoarthritis on MRI: The MOST Study
Journal of orthopaedic research, Vol.30(1), pp.1-8
01/2012
DOI: 10.1002/jor.21486
PMCID: PMC3217080
PMID: 21710542
Abstract
The sulcus angle has been widely used in the literature as a measure of trochlear morphology. Recently, lateral trochlear inclination and trochlear angle have been reported as alternatives. The purpose of this study was to determine the association between measures of trochlear morphology and patellofemoral joint (PFJ) cartilage damage and bone marrow lesions (BMLs). 907 knees were selected from the Multicenter Osteoarthritis Study, a cohort study of persons aged 50-79 years with or at risk for knee OA. Trochlear morphology was measured using lateral trochlear inclination, trochlear angle, and sulcus angle on axial MRI images; cartilage damage and BMLs were graded on MRI. We determined the association between quartiles of each trochlear morphology level with the presence or absence of cartilage damage and BMLs in the PFJ using logistic regression. The strongest associations were seen with lateral trochlear inclination and lateral PFJ cartilage damage and BMLs, with knees in the lowest quartile (flattened lateral trochlea) having more than two times the odds of lateral cartilage damage and BMLs compared to those in the highest quartile (p<0.0001). Lateral trochlear inclination may be the best method for assessment of trochlear morphology as it was strongly association with structural damage in the PFJ.
Details
- Title: Subtitle
- The association between measures of trochlear morphology and structural features of patellofemoral joint osteoarthritis on MRI: The MOST Study
- Creators
- J.J Stefanik - Boston University School of Medicine, Boston, MassachusettsF.W Roemer - Boston University School of Medicine, Boston, MassachusettsA.C Zumwalt - Boston University School of Medicine, Boston, MassachusettsYanyan Zhu - Boston University School of Medicine, Boston, MassachusettsK.D Gross - Boston University School of Medicine, Boston, MassachusettsJ.A Lynch - University of California, San Francisco, CAL.A Frey-Law - University of Iowa, Iowa City, IAC.E Lewis - University of Alabama, Birmingham, ALA Guermazi - Boston University School of Medicine, Boston, MassachusettsC.M Powers - University of Southern California, Los Angeles, CAD.T Felson - Boston University School of Medicine, Boston, Massachusetts
- Resource Type
- Journal article
- Publication Details
- Journal of orthopaedic research, Vol.30(1), pp.1-8
- DOI
- 10.1002/jor.21486
- PMID
- 21710542
- PMCID
- PMC3217080
- ISSN
- 0736-0266
- eISSN
- 1554-527X
- Grant note
- U01 AG018820-11 || AG / National Institute on Aging : NIA
- Language
- English
- Date published
- 01/2012
- Academic Unit
- Nursing; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984047720402771
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