Journal article
The association between patella alta and the prevalence and worsening of structural features of patellofemoral joint osteoarthritis: The Multicenter Osteoarthritis Study
Arthritis care & research (2010), Vol.62(9), pp.1258-1265
09/2010
DOI: 10.1002/acr.20214
PMCID: PMC2943040
PMID: 20506169
Abstract
Objective
To examine the relationship between patella alta and the prevalence and worsening at followup of structural features of patellofemoral joint (PFJ) osteoarthritis (OA) on magnetic resonance imaging (MRI).
Methods
The Multicenter Osteoarthritis Study is a cohort study of persons ages 50–79 years with or at risk for knee OA. Patella alta was measured using the Insall-Salvati ratio (ISR) on the baseline lateral radiograph, and cartilage damage, bone marrow lesions (BMLs), and subchondral bone attrition (SBA) were graded on MRI at baseline and at 30 months of followup in the PFJ. We examined the association of the ISR with the prevalence and worsening of cartilage damage, BMLs, and SBA in the PFJ using logistic regression.
Results
A total of 907 knees were studied (mean age 62 years, body mass index 30 kg/m2, ISR 1.10), 63% from female subjects. Compared with knees in the lowest ISR quartile at baseline, those in the highest quartile had 2.4 (95% confidence interval [95% CI] 1.7–3.3), 2.9 (95% CI 2.0–4.3), and 3.5 (95% CI 2.3–5.5) times the odds of having lateral PFJ cartilage damage, BMLs, and SBA, respectively, and 1.5 (95% CI 1.1–2.0), 1.3 (95% CI 0.9–1.8), and 2.2 (95% CI 1.4–3.4) times the odds of having medial PFJ cartilage damage, BMLs, and SBA, respectively. Similarly, those with high ISRs were also at risk for worsening of cartilage damage and BMLs over time than those with low ISRs.
Conclusion
A high ISR, indicative of patella alta, is associated with structural features of OA in the PFJ. Additionally, the same knees have an increased risk of worsening of these same features over time.
Details
- Title: Subtitle
- The association between patella alta and the prevalence and worsening of structural features of patellofemoral joint osteoarthritis: The Multicenter Osteoarthritis Study
- Creators
- J.J Stefanik - Boston University School of Medicine, Boston, MassachusettsA.C Zumwalt - Boston University School of Medicine, Boston, MassachusettsY Zhu - Boston University School of Medicine, Boston, MassachusettsK.D Gross - Boston University School of Medicine, Boston, MassachusettsM Clancy - Boston University School of Medicine, Boston, MassachusettsJ. A Lynch - UCSF, San Francisco, CAL.A Frey Law - UIowa, Iowa City, IAC.E Lewis - UAB, Birmingham, ALF.W Roemer - Boston University School of Medicine, Boston, MassachusettsC.M Powers - USC, Los Angeles, CAA Guermazi - Boston University School of Medicine, Boston, MassachusettsD.T Felson - Boston University School of Medicine, Boston, Massachusetts
- Resource Type
- Journal article
- Publication Details
- Arthritis care & research (2010), Vol.62(9), pp.1258-1265
- DOI
- 10.1002/acr.20214
- PMID
- 20506169
- PMCID
- PMC2943040
- NLM abbreviation
- Arthritis Care Res (Hoboken)
- ISSN
- 2151-464X
- eISSN
- 2151-4658
- Language
- English
- Date published
- 09/2010
- Academic Unit
- Nursing; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984047628702771
Metrics
24 Record Views