Journal article
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein
Cell, Vol.73(5), pp.999-1005
1993
DOI: 10.1016/0092-8674(93)90277-W
PMID: 8500185
Abstract
The small GTP-binding protein, ADP-ribosylation factor (ARF), has previously been shown to mediate the binding to Golgi membranes of the coatomer of nonclathrin-coated (COP-coated) vesicles. We now report that ARF is also required for the binding of the AP-1 adaptor protein of clathrin-coated vesicles to Golgi membranes. The binding of coat proteins from both clathrin- and COP-coated vesicles requires an additional Golgi membrane-associated factor. These results suggest that a mechanistic similarity underlies diverse types of vesicle coats.
Details
- Title: Subtitle
- The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein
- Creators
- Mark A. Stamnes - Memorial Sloan Kettering Cancer CenterJames E. Rothman - Memorial Sloan Kettering Cancer Center
- Resource Type
- Journal article
- Publication Details
- Cell, Vol.73(5), pp.999-1005
- DOI
- 10.1016/0092-8674(93)90277-W
- PMID
- 8500185
- NLM abbreviation
- Cell
- ISSN
- 0092-8674
- eISSN
- 1097-4172
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1993
- Academic Unit
- Molecular Physiology and Biophysics; Internal Medicine
- Record Identifier
- 9984297502902771
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