Journal article
The biochemistry and molecular biology of the dihydropyridine-sensitive calcium channel
Trends in Neurosciences, Vol.11(10), pp.425-430
1988
DOI: 10.1016/0166-2236(88)90193-2
PMID: 2469159
Abstract
Calcium channels are known to exist in muscle, neuronal and secretory cells. The 1,4-dihydropyridines are potent blockers of L-type Ca
2+ channels, and have been used as specific probes in the study of dihydropyridine-sensitive Ca
2+ channels. The receptor for the 1,4-dihydropyridines has been purified from skeletal muscle in order to characterize the biochemistry and molecular biology of the dihydropyridine-sensitive Ca
2+ channel. This review summarizes recent findings on the subunit composition of the dihydropyridinesensitive Ca
2+ channel, and discusses the structure and possible function of the individual subunits.
Details
- Title: Subtitle
- The biochemistry and molecular biology of the dihydropyridine-sensitive calcium channel
- Creators
- Kevin P CampbellAlbert T LeungAlan H Sharp
- Resource Type
- Journal article
- Publication Details
- Trends in Neurosciences, Vol.11(10), pp.425-430
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/0166-2236(88)90193-2
- PMID
- 2469159
- ISSN
- 0166-2236
- eISSN
- 1878-108X
- Language
- English
- Date published
- 1988
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Iowa Neuroscience Institute
- Record Identifier
- 9984020849702771
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