The cerebellum plays a role in conscious episodic memory retrieval

Nancy C Andreasen; Daniel S O'Leary; Sergio Paradiso; Ted Cizadlo; Stephan Arndt; G. Leonard Watkins; Laura L Boles Ponto; Richard D Hichwa

doi:10.1002/(SICI)1097-0193(1999)8:4<226::AID-HBM6>3.0.CO;2-4

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The cerebellum plays a role in conscious episodic memory retrieval

Journal article

Peer reviewed

The cerebellum plays a role in conscious episodic memory retrieval

Nancy C Andreasen, Daniel S O'Leary, Sergio Paradiso, Ted Cizadlo, Stephan Arndt, G. Leonard Watkins, Laura L Boles Ponto and Richard D Hichwa

Human brain mapping, Vol.8(4), pp.226-234

1999

DOI: 10.1002/(SICI)1097-0193(1999)8:4<226::AID-HBM6>3.0.CO;2-4

PMID: 10619416

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Abstract

The cerebellum has traditionally been considered to be primarily dedicated to motor functions. Its phylogenetic development and connectivity suggest, however, that it also may play a role in cognitive processes in the human brain. In order to examine a potential cognitive role for the cerebellum in human beings, a positron emission tomography (PET) study was conducted during a “pure thought experiment”: subjects intentionally recalled a specific past personal experience (consciously retrieved episodic memory). Since there was no motor or sensory input or output, the design eliminated the possibility that cerebellar changes in blood flow were due to motor activity. During silent recall of a consciously retrieved episodic memory, activations were observed in the right lateral cerebellum, left medial dorsal thalamus, medial and left orbital frontal cortex, anterior cingulate, and a left parietal region. These activations confirm a cognitive role for the cerebellum, which may participate in an interactive cortical‐cerebellar network that initiates and monitors the conscious retrieval of episodic memory. Hum. Brain Mapping 8:226–234, 1999. © 1999 Wiley‐Liss, Inc.

Cerebellum

episodic memory

P.E.T

cognition

neural circuits

Details

Title: Subtitle: The cerebellum plays a role in conscious episodic memory retrieval
Creators: Nancy C Andreasen
Daniel S O'Leary
Sergio Paradiso
Ted Cizadlo
Stephan Arndt
G. Leonard Watkins
Laura L Boles Ponto
Richard D Hichwa
Resource Type: Journal article
Publication Details: Human brain mapping, Vol.8(4), pp.226-234
DOI: 10.1002/(SICI)1097-0193(1999)8:4<226::AID-HBM6>3.0.CO;2-4
PMID: 10619416
NLM abbreviation: Hum Brain Mapp
ISSN: 1065-9471
eISSN: 1097-0193
Publisher: John Wiley & Sons, Inc; New York
Number of pages: 9
Grant note: NIMH (MH31593; MH40856; MHCRC43271) Research Scientist Award (MH00625) NARSAD, Established Investigator Award
Language: English
Date published: 1999
Academic Unit: Radiology; Psychiatry; Research Administration; Iowa Neuroscience Institute; Pharmaceutical Sciences and Experimental Therapeutics; Biostatistics; Physics and Astronomy; Radiation Oncology; Nursing; Injury Prevention Research Center
Record Identifier: 9984004195402771

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