Journal article
The correlation of voiding variables between non-instrumented uroflowmetery and pressure-flow studies in women with pelvic organ prolapse
Neurourology and urodynamics, Vol.27(6), pp.515-521
01/01/2008
DOI: 10.1002/nau.20568
PMID: 18551567
Abstract
Aims: To (1) correlate peak and maximum flow rates from non-instrumented flow (NIF) and pressure-flow studies (PFS) in women with pelvic organ prolapse (POP); (2) measure the impact of voided volume and degree of prolapse on correlations. Methods: We compared four groups of women with stages II-IV POP. Groups 1 and 2 were symptomatically stress continent women participating in the colpopexy and urinary reduction efforts (CARE) trial; during prolapse reduction before sacrocolpopexy, Group 1 (n = 67) did not have and Group 2 (n = 84) had urodynamic stress incontinence (USI). Group 3 (n 74) and Group 4 participants (n = 73), recruited specifically for this study, had stress urinary incontinence (SUI) symptoms. Group 3 planned sacrocolpopexy. Group 4 planned a different treatment option. Participants completed standardized uroflowmetry and pressure voiding studies. Results: Subjects' median age was 61 years; median parity 3% and 80% had stage III or IV POP. Based on the Blaivas-Groutz nomogram, 49% of all women were obstructed. NIF and PFS peak and average flow rates had low correlations with one another (0.31, P < 0.001 and 0.35, P < 0.001, respectively). When NIF and PFS voided volumes were within 25% of each other, the peak and average flow rate correlations improved (0.52, P < 0.001 and 0.57, P < 0.001, respectively). As vaginal prolapse increased, correlations between NIF and PFS peak and average flow rates decreased. Conclusion: Peak and average flow rates are highly dependent on voided volume in women with prolapse. As the prolapse stage increases, correlations between NIF and PFS variables decrease.
Details
- Title: Subtitle
- The correlation of voiding variables between non-instrumented uroflowmetery and pressure-flow studies in women with pelvic organ prolapse
- Creators
- Elizabeth Mueller - Loyola University Medical CenterJohn Wei - University of MichiganIngrid Nygaard - University of UtahLinda Brubaker - Loyola University Medical CenterEd Varner - University of Alabama at BirminghamAnthony Visco - University of North Carolina at Chapel HillGeoffrey W. Cundiff - Johns Hopkins MedicineAnne M. Weber - National Institute for Child Health and Human Development, National Institute of Health, Bethesda, MarylandChiara Ghetti - Magee-Womens HospitalKarl Kreder - University of IowaPelvic Floor Disorders Network
- Resource Type
- Journal article
- Publication Details
- Neurourology and urodynamics, Vol.27(6), pp.515-521
- DOI
- 10.1002/nau.20568
- PMID
- 18551567
- NLM abbreviation
- Neurourol Urodyn
- ISSN
- 0733-2467
- eISSN
- 1520-6777
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- U01HD041249 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) U10 HD41268; U10 HD41250; U10HD41261; U10 HD41267; U10 HD41269; U10 HD41248; U10 HD041261; U10 HD41263; U01 HD41249 / NICHD NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) U10HD041267 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
- Language
- English
- Date published
- 01/01/2008
- Academic Unit
- Obstetrics and Gynecology; Urology
- Record Identifier
- 9984383301202771
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