Journal article
The current clinical aspects of idiopathic portal hypertension
Intractable and rare disease research, Vol.2(3), pp.94-97
08/2013
DOI: 10.5582/irdr.2013.v2.3.94
PMCID: PMC4204548
PMID: 25343110
Abstract
Idiopathic portal hypertension (IPH) comprises disorders developing increased portal pressure in the absence of cirrhosis: the clear mechanisms to explain this disease are still not well recognized. IPH usually suggests a benign prognosis, but sometimes is complicated with severe hemorrhage due to ruptured esophageal varices, or massive splenomegaly. Conventional treatments for those complications for patients with cirrhosis usually works when diverted to patients with IPH, although some of those patients might require liver transplantation if the treatment fails. However, there are few consistent treatment strategies for IPH itself, its complications or the indications for liver transplantation. In this mini review, we summarize the clinical manifestations and several potential theories to explain the etiology, as well as the current treatment options for IPH.
Details
- Title: Subtitle
- The current clinical aspects of idiopathic portal hypertension
- Creators
- Tomohiro Tanaka - Organ Transplantation Service, The University of Tokyo Hospital, Tokyo, JapanYasuhiko Sugawara - Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanNorihiro Kokudo - Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
- Resource Type
- Journal article
- Publication Details
- Intractable and rare disease research, Vol.2(3), pp.94-97
- Publisher
- International Research and Cooperation Association for Bio & Socio-Sciences Advancement
- DOI
- 10.5582/irdr.2013.v2.3.94
- PMID
- 25343110
- PMCID
- PMC4204548
- ISSN
- 2186-3644
- eISSN
- 2186-361X
- Language
- English
- Date published
- 08/2013
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984094363102771
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