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The effect of ejaculatory abstinence time on in vitro fertilization outcomes
Journal article   Open access   Peer reviewed

The effect of ejaculatory abstinence time on in vitro fertilization outcomes

Emily Capper, Karen Summers, Amy Sparks, Emily Jacobs and Bradley Van Voorhis
F&S Reports (Online), Vol.6(2), pp.227-229
06/2025
DOI: 10.1016/j.xfre.2025.03.003
PMCID: PMC12223564
PMID: 40620363
url
https://doi.org/10.1016/j.xfre.2025.03.003View
Published (Version of record) Open Access

Abstract

To determine if the ejaculatory abstinence affects the fertilization rate in vitro fertilization cycles Retrospective cohort study Patients undergoing their first IVF cycle using standard insemination or ICSI insemination from January 2021 to January 2022 Intervention (for RCT) or Exposure (for observational studies): Fertilization rate Despite higher semen analysis parameters with longer ejaculatory abstinence up to 7 days, there was no effect of increasing ejaculatory abstinence on either intracytoplasmic sperm injection or standard insemination fertilization rates. There were also no significant differences in clinical pregnancy, live birth, and miscarriage rates with increasing time of ejaculatory abstinence Increase in days of abstinence up to seven days prior to providing a semen sample for IVF is associated with an increase in semen volume, sperm concentration and total motile sperm count. Despite improved semen parameters with increasing days of abstinence, there was no difference in fertilization rates with either ICSI or standard insemination
 ejaculatory abstinence fertilization ICSI IVF live birth

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