The effect of intracanal anti-inflammatory medicaments on external root resorption of replanted dog teeth after extended extra-oral dry time

H Chen; F B Teixeira; A L Ritter; L Levin; M Trope

doi:10.1111/j.1600-9657.2006.00483.x

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The effect of intracanal anti-inflammatory medicaments on external root resorption of replanted dog teeth after extended extra-oral dry time

Journal article

Peer reviewed

The effect of intracanal anti-inflammatory medicaments on external root resorption of replanted dog teeth after extended extra-oral dry time

H Chen, F B Teixeira, A L Ritter, L Levin and M Trope

Dental traumatology, Vol.24(1), pp.74-78

02/2008

DOI: 10.1111/j.1600-9657.2006.00483.x

PMID: 18173671

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Abstract

The prognosis of replanted teeth depends on several factors, the most important being the length of extra-oral dry time. Studies show that after 60 min dry time, root resorption is predicted. Immediate intracanal placement of Ledermix, a paste containing triamcinolone (corticosteroid) and demeclocycline (tetracycline) has been shown to inhibit root resorption after extended dry time. However, discoloration is possible from the tetracycline in Ledermix. To evaluate the individual influence of corticosteroid and tetracycline on external root resorption after extended extra-oral dry time. Sixty-nine premolar roots of four beagle dogs were extracted and instrumented with NiTi files. Group 1 (negative control) was immediately replanted after root filling with GP and sealer; Group 2 (positive control) was root filled with GP and sealer and replanted after 60 min dry time; In groups 3-5, the canals were filled with Ledermix, Triamcinolone, and Demeclocycline, respectively, and replanted after 60 min dry time. After 4 months, the dogs were sacrificed and the roots were examined histologically for type of healing (favorable or unfavorable) and remaining root diameter. The groups treated with Ledermix, Triamcinolone and Demeclocycline had statistically significantly more favorable healing (75.8%; 69.8%; 52.4%) and more remaining root structure (5.59; 5.48; 5.09) than the group filled with GP and sealer (positive control) (0; 1.15). Corticosteroids were as effective as Ledermix at inhibiting external root resorption.

Dental Alloys

Glucocorticoids - therapeutic use

Demeclocycline - therapeutic use

Gutta-Percha - therapeutic use

Time Factors

Anti-Inflammatory Agents - therapeutic use

Titanium

Root Canal Preparation - instrumentation

Root Canal Filling Materials

Wound Healing - drug effects

Disease Models, Animal

Desiccation

Triamcinolone Acetonide - therapeutic use

Root Canal Irrigants - therapeutic use

Root Canal Preparation - methods

Tooth Avulsion - therapy

Root Resorption - prevention & control

Animals

Dogs

Epoxy Resins - therapeutic use

Tooth Replantation

Nickel

Drug Combinations

Edetic Acid - therapeutic use

Sodium Hypochlorite - therapeutic use

Tooth Avulsion - physiopathology

Details

Title: Subtitle: The effect of intracanal anti-inflammatory medicaments on external root resorption of replanted dog teeth after extended extra-oral dry time
Creators: H Chen - Private Practice, Durham, NC, USA
F B Teixeira
A L Ritter
L Levin
M Trope
Resource Type: Journal article
Publication Details: Dental traumatology, Vol.24(1), pp.74-78
Publisher: Denmark
DOI: 10.1111/j.1600-9657.2006.00483.x
PMID: 18173671
ISSN: 1600-4469
eISSN: 1600-9657
Language: English
Date published: 02/2008
Academic Unit: Preventive and Community Dentistry; Endodontics
Record Identifier: 9984066097102771

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