Journal article
The effect of surgical sterilization on ovarian function: a rat model
European journal of obstetrics & gynecology and reproductive biology, Vol.100(2), pp.204-207
2002
DOI: 10.1016/S0301-2115(01)00481-X
PMID: 11750966
Abstract
Objective: To evaluate the effects of various methods of sterilization on ovarian function, in a rat model. Study Design: Forty-eight female Whistar albino rats weighing 200-250g are divided equally into four groups. All rats underwent laparotomy, while no specific intervention was made to the first group. Bilateral tubal ligation by Pomeroy's technique, unipolar and bipolar cautery was done to the second, third and fourth groups, respectively. All rats were then individually caged and fed on demand for 6 months. Afterwards, the rats were sacrificed and underwent bilateral oophorectomy. A pathologist blinded to the groups made histological examination by counting number of healthy tertiary follicles and corpora lutea in each ovary. The results of the groups were statistically compared by one-way ANOVA using post-hoc Bonferroni correction. Results: Rats in group 1 had significantly higher number of healthy tertiary follicles than every other group. Rats in group 1 also had significantly more corpora lutea than those in group 3. Conclusion: Tubal ligation may affect ovarian function, which in turn may reflect to ovarian histology in rats. © 2002 Elsevier Science Ireland Ltd. All rights reserved.
Details
- Title: Subtitle
- The effect of surgical sterilization on ovarian function: a rat model
- Creators
- Esra Kuscu - Başkent UniversityHakan E Duran - Başkent UniversityHulusi B Zeyneloglu - Başkent UniversityBeyhan Demirhan - Başkent UniversityTayfun Bagis - Başkent UniversityEsra Saygili - Başkent University
- Resource Type
- Journal article
- Publication Details
- European journal of obstetrics & gynecology and reproductive biology, Vol.100(2), pp.204-207
- Publisher
- Elsevier
- DOI
- 10.1016/S0301-2115(01)00481-X
- PMID
- 11750966
- ISSN
- 0301-2115
- eISSN
- 1872-7654
- Language
- English
- Date published
- 2002
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9984315750802771
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