Journal article
The effective dynamic ranges for glaucomatous visual field progression with standard automated perimetry and stimulus sizes III and V
Investigative Ophthalmology and Visual Science, Vol.59(1), pp.439-445
2018
DOI: 10.1167/iovs.17-22390
PMCID: PMC5777662
PMID: 29356822
Abstract
Purpose: It has been shown that threshold estimates below approximately 20 dB have little effect on the ability to detect visual field progression in glaucoma. We aimed to compare stimulus size V to stimulus size III, in areas of visual damage, to confirm these findings by using (1) a different dataset, (2) different techniques of progression analysis, and (3) an analysis to evaluate the effect of censoring on mean deviation (MD).Methods: In the Iowa Variability in Perimetry Study, 120 glaucoma subjects were tested every 6 months for 4 years with size III SITA Standard and size V Full Threshold. Progression was determined with three complementary techniques: pointwise linear regression (PLR), permutation of PLR, and linear regression of the MD index. All analyses were repeated on "censored'' datasets in which threshold estimates below a given criterion value were set to equal the criterion value.Results: Our analyses confirmed previous observations that threshold estimates below 20 dB contribute much less to visual field progression than estimates above this range. These findings were broadly similar with stimulus sizes III and V.Conclusions: Censoring of threshold values < 20 dB has relatively little impact on the rates of visual field progression in patients with mild to moderate glaucoma. Size V, which has lower retest variability, performs at least as well as size III for longitudinal glaucoma progression analysis and appears to have a larger useful dynamic range owing to the upper sensitivity limit being higher.
Details
- Title: Subtitle
- The effective dynamic ranges for glaucomatous visual field progression with standard automated perimetry and stimulus sizes III and V
- Creators
- Michael WallGideon K.D ZambaPaul H Artes
- Resource Type
- Journal article
- Publication Details
- Investigative Ophthalmology and Visual Science, Vol.59(1), pp.439-445
- DOI
- 10.1167/iovs.17-22390
- PMID
- 29356822
- PMCID
- PMC5777662
- NLM abbreviation
- Invest Ophthalmol Vis Sci
- ISSN
- 0146-0404
- eISSN
- 1552-5783
- Language
- English
- Date published
- 2018
- Academic Unit
- Neurology; Radiology; Biostatistics; Ophthalmology and Visual Sciences
- Record Identifier
- 9983980079802771
Metrics
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