The effects of localized cold work on the heating characteristics of thermal therapy implants

Uyen T LE; Robert D TUCKER; Joon B PARK

doi:10.1002/jbm.10041

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Journal article

The effects of localized cold work on the heating characteristics of thermal therapy implants

Uyen T LE, Robert D TUCKER and Joon B PARK

Journal of biomedical materials research, Vol.63(1), pp.24-30

2002

DOI: 10.1002/jbm.10041

PMID: 11787025

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Abstract

The use of cylindrical palladium-cobalt alloy rods has proven effective in the clinical ablation of prostate cancer. In order to thermally destroy tissue, the ferromagnetic implants must heat to temperatures greater than 42 degrees C and produce a power output of at least 400 mW. However, localized cold work such as bending may effect the heating characteristics of these rods and have detrimental clinical effect. Three different types of test devices were manufactured to introduce cold work at one point in the implant: a sharp bend, a curvature, and an MTS three-point bend. After bending, each rod was then restraightened. Rod power output before and after bending was measured by calorimetry. Statistical comparison of power output for prebent and restraightened rods versus degrees bent was performed through the use of the SAS MIXED procedure to fit a mixed-model repeated-measures ANOVA with the use of multivariate models. In vitro testing showed that there was only a small change in the power output before and after rods were cold worked regardless of the type of bending. Therefore, localized cold work does not affect the clinical heating characteristics of rods.

Biological and medical sciences

Medical sciences

Diseases of the urinary system

Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)

Technology. Biomaterials. Equipments. Material. Instrumentation

Details

Title: Subtitle: The effects of localized cold work on the heating characteristics of thermal therapy implants
Creators: Uyen T LE - Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States
Robert D TUCKER - Department of Pathology, University of Iowa, Iowa City, Iowa, United States
Joon B PARK - Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States
Resource Type: Journal article
Publication Details: Journal of biomedical materials research, Vol.63(1), pp.24-30
Publisher: John Wiley & Sons; New York, NY
DOI: 10.1002/jbm.10041
PMID: 11787025
ISSN: 0021-9304
eISSN: 1097-4636
Language: English
Date published: 2002
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Pathology
Record Identifier: 9984047778802771

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