Journal article
The efficacy of carbomer based and lipid containing eye gel in the treatment of dry eye
Medical journal of Bakirköy, Vol.13(2), pp.73-76
06/22/2017
DOI: 10.5350/BTDMJB201713203
Abstract
Objective: The aim of this study was to assess the effect of the carbomer-based lipid-containing (CBLC) gel on tear break-up time (TBUT), Schirmer's score, and ocular surface disease index (OSDI) through a one-masked clinical trial in patients with dry eye syndrome.
Material and Methods: A 4-week and retrospective study was conducted. A total of 60 eyes of 30 patients with mild to moderate dry eye syndrome were included and treated with the CBLC gel two times a day within twelve hours interval. The primary end point was global assessment of study treatment by the patients before treatment and at the end of a 4-week treatment. All patients met the diagnostic criteria of impaired tear function and ocular surface abnormalities. Outcomes measured at baseline and at the end of the 4-week treatment included Schirmer's test, TBUT, and OSDI values.
Results: The mean age of 30 patients was 53.79 +/- 12.73 years. At baseline, the mean for TBUT was 5.03 +/- 1.04 second and 9.81 +/- 4.95 mm for Schirmer's test. The TBUT score increased to a mean of 8.12 +/- 1.61 second and the Schirmer's test score increased to a mean of 13.15 +/- 5.08 mm after the 4-week treatment. Subjective patient assessment was better after the treatment, the mean for the OSDI score was 50.59%+/- 13.29% at baseline and 36.86%+/- 11.93% after the 4-week treatment. These changes for TBUT, Schirmer's test, and OSDI scores were statistically significant (p<0.05).
Conclusion: CBLC gel is an effective treatment option for the patients who have suffered from mild to moderate dry eye syndrome.
Details
- Title: Subtitle
- The efficacy of carbomer based and lipid containing eye gel in the treatment of dry eye
- Creators
- Cetin Akpolat - Okmeydani Egitim & Arastirma Hastanesi, Goz Hastalikiari Bolumu, Istanbul, TurkeyFerhat Evliyaoglu - Okmeydani Egitim & Arastirma Hastanesi, Goz Hastalikiari Bolumu, Istanbul, TurkeyMuhammed Mustafa Kurt - Okmeydani Egitim & Arastirma Hastanesi, Goz Hastalikiari Bolumu, Istanbul, TurkeyHatice Karahan - Okmeydani Egitim & Arastirma Hastanesi, Goz Hastalikiari Bolumu, Istanbul, TurkeyMustafa Nuri Elcioglu - Okmeydani Egitim & Arastirma Hastanesi, Goz Hastalikiari Bolumu, Istanbul, Turkey
- Resource Type
- Journal article
- Publication Details
- Medical journal of Bakirköy, Vol.13(2), pp.73-76
- Publisher
- Yerkure Tanitim & Yayincilik Hizmetleri A S
- DOI
- 10.5350/BTDMJB201713203
- ISSN
- 1305-9319
- eISSN
- 1305-9327
- Number of pages
- 4
- Language
- English; Turkish
- Date published
- 06/22/2017
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984845249602771
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