Journal article
The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
PLoS biology, Vol.19(4), pp.e3001217-e3001217
04/2021
DOI: 10.1371/journal.pbio.3001217
PMCID: PMC8101996
PMID: 33901166
Abstract
What transpires soon after inhaling Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the respiratory virus causing Coronavirus Disease 2019 (COVID-19)? Where does infection begin? What are the features of subsequent virus spread? How might host responses quickly contain infection? Two recently published manuscripts have evaluated infection in primary cultures of well-differentiated cells to address these questions and bring more light on the proviral and antiviral components operating during the initial days after SARS-CoV-2 exposure.
Details
- Title: Subtitle
- The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
- Creators
- Tom Gallagher - Loyola University ChicagoPaul B McCray Jr - Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America
- Resource Type
- Journal article
- Publication Details
- PLoS biology, Vol.19(4), pp.e3001217-e3001217
- DOI
- 10.1371/journal.pbio.3001217
- PMID
- 33901166
- PMCID
- PMC8101996
- NLM abbreviation
- PLoS Biol
- ISSN
- 1544-9173
- eISSN
- 1545-7885
- Grant note
- P01 AI060699 / NIAID NIH HHS
- Language
- English
- Date published
- 04/2021
- Academic Unit
- Microbiology and Immunology; Pulmonary Medicine; Stead Family Department of Pediatrics; Internal Medicine
- Record Identifier
- 9984297322102771
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